Rabbit Anti-FMO1 Antibody (MO-DKB-01318W)


Cat: MO-DKB-01318W
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Specifications

Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivityHuman (Homo sapiens), Rhesus (Macaca mulatta)
ImmunogenA recombinant protein containing sequences in the central region of human FMO1.
EpitopeThe epitope is in the Center of FMO1.
FormatLiquid or Lyophilized
Buffer0.1M Tris, pH 7, 0.1M Glycine, 20% Glycerol
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurityAffinity purified
Cellular LocalizationMicrosome membrane, Endoplasmic reticulum membrane

Application Information

ApplicationWB, IF
Application NotesWestern Blot 1:500-1:3000
Immunocytochemistry/Immunofluorescence 1:100-1:1000

Target

IntroductionMetabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]
Product OverviewThis product is a Rabbit antibody against the Center of the FMO1. It can be used for FMO1 detection in Western Blot, Immunofluorescence.
Alternative NamesFlavin Containing Monooxygenase 1; EC 1.14.13.8; Fetal Hepatic Flavin-Containing Monooxygenase 1; Dimethylaniline Oxidase 1; FMO 1;
Gene ID2326
UniProt IDQ01740
For Research Use Only | Not For Clinical Use.
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