Mouse Anti-Frog adrb2 Antibody (MO-AB-01278H)


Cat: MO-AB-01278H
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityFrog (Xenopus laevis)
CloneMO01278C
SpecificityThis antibody binds to Frog adrb2.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationPlasma membrane; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThis gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.
Product OverviewThis product is a mouse antibody against adrb2. It can be used for adrb2 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesMGC80764 protein; adrb2; MGC80764
UniProt IDQ6GP00
Protein RefseqThe length of the protein is 426 amino acids long.
The sequence is show below: MERSVSASPNSSSSLLYQLVTTVSNNSSSNTTAAAKVKPSDAWMVVMGIVMSCIVLVIVFGNVLVIVAIAKFQRLQTVTNYFITSLACADLLMGLMVVPFGASSIILDTWVFNNFWCEFWTSVDILCVTASIETLCVIAVDRYFAITSPFRYQSLLTKCKARIVILLVWLVSTLTSFLPICMHWYRIDEKVAMDCYAEPTCCFFHTNRAYAISSSIISFYLPLVVMIFVYSRVFQEAKKQLKKIDKSEGRFHNQNNQQDANGKQGNRRSSKFWLKEHKALKTLGIIMGTFTLCWLPFFIVNIVQGMHKDIIPVDVYTFLNWVGYVNSAFNPLIYCRSPDFRFTFQELLCLRKPGSKAYTNGYPQSNGNSAYNEDTETCQYSKDRTCEVLFKEEETPNPSLLNCEGTLLDFSLDPLGKNHNTHDCLL.
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For Research Use Only | Not For Clinical Use.
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