Mouse Anti-Frog pdk1 Antibody (MO-AB-06147H)


Cat: MO-AB-06147H
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityFrog (Xenopus laevis)
CloneMO06147C
SpecificityThis antibody binds to Frog pdk1.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationMitochondrion

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionPyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene.
Product OverviewThis product is a mouse antibody against pdk1. It can be used for pdk1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesMGC81400 protein; pdk1; MGC81400
UniProt IDQ6IR88
Protein RefseqThe length of the protein is 412 amino acids long.
The sequence is show below: MRLLRALMRSAPLSSRNTPSLVDFYSKFSPSPLSMKQFLDFGSVNACEKTSFIFLRHELPVRLANIMKEINLLPDNLLKMPSIKLVQSWYVQSFQEIIDFKDTNAEDLNTVQKFTDTVITIRNRHNDVIPTMAQGVVEFKDSFGVDPVTSQNVQYFLDRFYMSRISIRMLLNQHTLLFGGEVKVNPAHPKHIGSIDPACNVVDVVKDGYENAKHLCDLYYMSSPELELTEFNAKSPGQPIQVVYVPSHLYHMVFELFKNAMRATMEFQADKGVYPPIKVHVVLGSEDLTVKLSDRGGGVPLRKIERLFNYMYSTAPLPRMETSRATPLAGFGYGLPISRLYAKYFQGDLKLYSLEGYGTDAVIYFKALSTESVERLPVYNKSAWKHYKTNHEADDWCVPSSEPKDMTTFRSN.
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For Research Use Only | Not For Clinical Use.
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