Mouse Anti-Frog pdp1 Antibody (MO-AB-06155H)


Cat: MO-AB-06155H
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Size:
Conjugate:
 Inquiry
  • Product Details

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityFrog (Xenopus laevis)
CloneMO06155C
SpecificityThis antibody binds to Frog pdp1.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionPyruvate dehydrogenase (E1) is one of the three components (E1, E2, and E3) of the large pyruvate dehydrogenase complex. Pyruvate dehydrogenase kinases catalyze phosphorylation of serine residues of E1 to inactivate the E1 component and inhibit the complex. Pyruvate dehydrogenase phosphatases catalyze the dephosphorylation and activation of the E1 component to reverse the effects of pyruvate dehydrogenase kinases. Pyruvate dehydrogenase phosphatase is a heterodimer consisting of catalytic and regulatory subunits. Two catalytic subunits have been reported; one is predominantly expressed in skeletal muscle and another one is is much more abundant in the liver. The catalytic subunit, encoded by this gene, is the former, and belongs to the protein phosphatase 2C (PP2C) superfamily. Along with the pyruvate dehydrogenase complex and pyruvate dehydrogenase kinases, this enzyme is located in the mitochondrial matrix. Mutation in this gene causes pyruvate dehydrogenase phosphatase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Product OverviewThis product is a mouse antibody against pdp1. It can be used for pdp1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesMGC82628 protein; pdp1; MGC82628
UniProt IDQ66J23
Protein RefseqThe length of the protein is 528 amino acids long.
The sequence is show below: MSAPTRLLFPLIRNCEFGRICSSVCYCHHKHLCCSSSHSSFKLGADTRHVSAFHNPRCTQVRRYVTTPQRFYLTPPQVNSILKANEYSFKVPEFDGKNISSILGFDSNQLPANAPIEDRRSAATCLQSRGMLLGVFDGHAGCACAQAVSERLFYYIAVSLLPQETLLEIENAVESGRALLPILQWHKHPNDYFSKEASKMYFNSLRTYWQELIDLNTGETTDVKEALINSFKRLDNDLSLEAQVGDPNSFLNYWVLRVAFSGATACVAHVDGVDLHVANTGDSRALLGVQEEDGSWSAVTMSHDHNAQNESEIIRVKSEHPKEVKTIVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVVESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVIYHRLRPKDKFLILATDGLWETMHRQDVVRIVGEYLTGVHHQQPLAVGGYKVTLGQMQGLLMERRARTSSMFEDQNAATHLIRHAVGNNEFGAVDHERLSKMLSLPEELARMYRDDITILVVQFNSHVIGAHQNKDQ.
For Research Use Only | Not For Clinical Use.
Online Inquiry