Mouse Anti-Gad1 Antibody (CBMOAB-17143FYA)


Cat: CBMOAB-17143FYA
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  • Specifications
  • Application Information
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Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-17143FYA Monoclonal Fruit fly (Drosophila melanogaster), A. thaliana (Arabidopsis thaliana), Cat (Felis catus), Dog (Canis lupus familiaris), Marmoset, Rat (Rattus norvegicus), Rhesus (Macaca mulatta), Yeast WB, ELISA MO17143FYA 100 µg
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CBMOAB-33667FYC Monoclonal A. thaliana (Arabidopsis thaliana) WB, ELISA MO33667FC 100 µg
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CBMOAB-43299FYA Monoclonal Rhesus (Macaca mulatta) WB, ELISA MO43299FYA 100 µg
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CBMOAB-01423CR Monoclonal Yeast WB, ELISA MO01423CR 100 µg
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MO-AB-08098W Monoclonal Cat (Felis catus) WB, ELISA MO08098W 100 µg
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MO-AB-30868W Monoclonal Dog (Canis lupus familiaris) WB, ELISA MO30868W 100 µg
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MO-AB-55794W Monoclonal Marmoset WB, ELISA MO55794W 100 µg
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MO-AB-25929H Monoclonal Rat (Rattus norvegicus) WB, ELISA MO25929C 100 µg
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityFruit fly (Drosophila melanogaster), A. thaliana (Arabidopsis thaliana), Cat (Felis catus), Dog (Canis lupus familiaris), Marmoset, Rat (Rattus norvegicus), Rhesus (Macaca mulatta), Yeast
CloneMO17143FYA
SpecificityThis antibody binds to fruit fly Gad1.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationCytosol

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThis gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.
Product OverviewMouse Anti-D. melanogaster Gad1 Antibody is a mouse antibody against Gad1. It can be used for Gad1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesGlutamate decarboxylase; GAD; EC 4.1.1.15; Gad1; Gad Glb
UniProt IDP20228
Protein RefseqThe length of the protein is 510 amino acids long.
The sequence is show below: MSLNPNGYKLSERTGKLTAYDLMPTTVTAGPETREFLLKVIDVLLDFVKATNDRNEKVLDFHHPEDMKRLLDLDVPDRALPLQQLIEDCATTLKYQVKTGHPHFFNQLSNGLDLISMAGEWLTATANTNMFTYEIAPVFILMENVVLTKMREIIGWSGGDSILAPGGSISNLYAFLAARHKMFPNYKEHGSVGLPGTLVMFTSDQCHYSIKSCAAVCGLGTDHCIVVPSDEHGKMITSELERLILERKAKGDIPFFVNATAGTTVLGAFDDINTIADICQKYNCWMHIDAAWGGGLLMSRKHRHPRFTGVERADSVTWNPHKLMGALLQCSTIHFKEDGLLISCNQMSAEYLFMTDKQYDISYDTGDKVIQCGRHNDIFKLWLQWRAKGTEGFEQQQDRLMELVQYQLKRIREQSDRFHLILEPECVNVSFWYVPKRLRGVPHDAKKEVELGKICPIIKGRMMQKGTLMVGYQPDDRRPNFFRSIISSAAVNEADVDFMLDEIHRLGDDL.
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For Research Use Only | Not For Clinical Use.
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