Mouse Anti-GAD1 Antibody (Full-length)

Cat: MO-NAB-00385W
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Host speciesMouse (Mus musculus)
Species ReactivityHuman (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Primate, Zebrafish (Danio rerio)
SpecificityThis antibody is binds to Human GAD1 and has cross reactivity with Mouse, Rat, Primate, Zebrafish.
ImmunogenA full-length human recombinant protein of human GAD1 (NP_000808) produced in HEK293T cells.
EpitopeThe epitope is in the Full-length of GAD1.
FormatLiquid or Lyophilized
BufferPBS, pH 7.3, 1.0% BSA, 50% Glycerol.
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurificationImmunogen affinity purified

Application Information

ApplicationWB, IF, IHC, IHC-P, IP, PEP-ELISA
Application NotesWestern Blot: 1:1000-2000
Immunofluorescence: 1:50
Immunohistochemistry: 1:50
Immunohistochemistry-Paraffin: 1:50
Immunoprecipitation: 4 ug/mL


IntroductionThis gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.
Product OverviewThis product is a Mouse antibody against the Full-length of the GAD1. It can be used for GAD1 detection in Western Blot, Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, PEP-Enzyme-Linked Immunosorbent Assay.
Alternative NamesGlutamate Decarboxylase 1; Glutamate Decarboxylase 1 (Brain; 67kDa); Glutamate Decarboxylase 67 KDa Isoform; 7 KDa Glutamic Acid Decarboxylase; EC; GAD-67; GAD
Gene ID2571(Human); 14415(Mouse); 24379(Rat)
UniProt IDQ99259(Human); P48318(Mouse); P18088(Rat)
For Research Use Only | Not For Clinical Use.
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