Mouse Anti-GAD1 Antibody (Full-length)
Cat: MO-NAB-00385W
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Primate, Zebrafish (Danio rerio) |
| Clone | NW0310 |
| Specificity | This antibody is binds to Human GAD1 and has cross reactivity with Mouse, Rat, Primate, Zebrafish. |
| Immunogen | A full-length human recombinant protein of human GAD1 (NP_000808) produced in HEK293T cells. |
| Epitope | The epitope is in the Full-length of GAD1. |
| Format | Liquid or Lyophilized |
| Buffer | PBS, pH 7.3, 1.0% BSA, 50% Glycerol. |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purification | Immunogen affinity purified |
Application Information
| Application | WB, IF, IHC, IHC-P, IP, PEP-ELISA |
| Application Notes | Western Blot: 1:1000-2000 Immunofluorescence: 1:50 Immunohistochemistry: 1:50 Immunohistochemistry-Paraffin: 1:50 Immunoprecipitation: 4 ug/mL |
Target
| Introduction | This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form. |
| Product Overview | This product is a Mouse antibody against the Full-length of the GAD1. It can be used for GAD1 detection in Western Blot, Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, PEP-Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Glutamate Decarboxylase 1; Glutamate Decarboxylase 1 (Brain; 67kDa); Glutamate Decarboxylase 67 KDa Isoform; 7 KDa Glutamic Acid Decarboxylase; EC 4.1.1.15; GAD-67; GAD |
| Gene ID | 2571(Human); 14415(Mouse); 24379(Rat) |
| UniProt ID | Q99259(Human); P48318(Mouse); P18088(Rat) |
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For Research Use Only | Not For Clinical Use.
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