Mouse Anti-Goat TLR4 Antibody (MO-AB-38311W)


Cat: MO-AB-38311W
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityGoat (Capra hircus)
CloneMO38311W
SpecificityThis antibody binds to Goat TLR4.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThe protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.
Product OverviewMouse Anti-Goat TLR4 Antibody is a mouse antibody against TLR4. It can be used for TLR4 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesToll-like receptor; TLR4
UniProt IDE5FXB8
Protein RefseqThe length of the protein is 841 amino acids long.
The sequence is show below: MMARARRAAALIPAMAILSCLRTESWDPCVQVVPNISYQCMELNLYKIPDNIPVSTEMLDLSFNYLRHLGSHNFSRFPELQVLDLSRCEIKIIEDNTFQGLNHLSTLILTGNPIQSLAWGAFSGLSSLQKLVAVETNLVSLDDFPIGHLKTLKELNVAHNFIHSFKLPEYFSNLPNLEHLDLSNNKIQNIYYEDVKVLHQMPLLNLSLDLSLNPLEFIEPGTFKEIKLNGLTLRSNFNSSYVMKTCIQGLAGLKINRLVLGEFKNERKLQKFDRSCLEGLCNLTIEQFRIAYLNKFSRNDTDLFNCLANVSMISLLSIPLGSLQALLKDFRWQHLEMINCDFDKFPALELRSLKKFVFTDNKDVSSFTKTELPSLQYLDLKRNHLSFKTCCSHTDFGTTNLKHLDLSFNDVITLSSNFMGLEQLEHLDFQHSTLKQINAFSTFLSLRNLRYLDISYTNIRIVFHGIFTGLVSLQTLKMAGNSFQNNLLPDIFTELTNLTILDLSKCQLEQVSWTAFHSLPSLQVLNMSHNKLLSLDTFLYEPLHSLRILDCSFNRITASKEQELRSLPRNLTWLNLTQNEFACVCEHQSFLQWVKDQRQLLVGAEQMMCAEPLDVKDMPVLGFRNATCQMSKTIISVSVVTVLLVSVVGVLVYKFYFHLMLLAGCKKYGRGESTYDAFVIYSSQDEAWVRNELVKNLEEGVPPFQLCLHYRDFIPGVAIAANIIQEGFHKSRKVIVVVSQHFIQSRWCIFEYEIAQTWQFLSSRAGIIFIVLQKLEKSLLRQQVELYRLLNRNTYLEWEDSVLGRHVFWRRLRKALLAGKPRSPEGTADAETNPQEATTST.
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For Research Use Only | Not For Clinical Use.
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