Rabbit Anti-GPX2 Antibody (MO-DKB-00678W)
Cat: MO-DKB-00678W
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
| Size: | |
| Conjugate: | |
| Inquiry |
- Product Details
Specifications
| Host species | Rabbit (Oryctolagus cuniculus) |
| Species Reactivity | Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Pig (Sus scrofa), Bovine (Bos taurus), Dog (Canis lupus familiaris), Primat, Rhesus (Macaca mulatta) |
| Immunogen | A synthetic peptide containing sequences within the C-terminal region of human GPX2. |
| Epitope | The epitope is in the C-terminal of GPX2. |
| Format | Liquid or Lyophilized |
| Buffer | PBS, pH 7, 20% Glycerol |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | Affinity purified |
| Cellular Localization | Cytoplasm |
Application Information
| Application | WB, IHC, IHC-P, IP |
| Application Notes | Western Blot 1:500-1:10000 Immunohistochemistry 1:100-1:1000 Immunohistochemistry-Paraffin 1:100-1:1000 Immunoprecipitation 1:100-1:500 |
Target
| Introduction | The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione, and thereby protect cells against oxidative damage. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme is predominantly expressed in the gastrointestinal tract (also in liver in human), is localized in the cytoplasm, and whose preferred substrate is hydrogen peroxide. Overexpression of this gene is associated with increased differentiation and proliferation in colorectal cancer. This isozyme is also a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2016] |
| Product Overview | This product is a Rabbit antibody against the C-terminal of the GPX2. It can be used for GPX2 detection in Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation. |
| Alternative Names | Glutathione Peroxidase 2; Glutathione Peroxidase 2 (Gastrointestinal); Glutathione Peroxidase-Related Protein 2; Gastrointestinal Glutathione Peroxidase; EC 1.11.1.9; GSHPX-GI; GSHPx-2; GPRP-2; |
| Gene ID | 2877 |
| UniProt ID | P18283 |
See other products for " GPX2 "
| MO-AB-00580L | Mouse Anti-Elephant GPX2 Antibody (MO-AB-00580L) |
| MO-AB-11931W | Mouse Anti-Chimpanzee GPX2 Antibody (MO-AB-11931W) |
| MO-AB-33270H | Mouse Anti-Nile tilapia GPX2 Antibody (MO-AB-33270H) |
| MO-DKB-01993W | Rabbit Anti-GPX2 Antibody (MO-DKB-01993W) |
| CBMOAB-34189FYC | Mouse Anti-Arabidopsis GPX2 Antibody (CBMOAB-34189FYC) |
| MO-AB-26220R | Mouse Anti-Pig GPX2 Antibody (MO-AB-26220R) |
| MO-AB-06534Y | Mouse Anti-O. anatinus GPX2 Antibody (MO-AB-06534Y) |
| CBMOAB-01573CR | Mouse Anti-Yeast GPX2 Antibody (CBMOAB-01573CR) |
| MO-AB-31014W | Mouse Anti-Dog GPX2 Antibody (MO-AB-31014W) |
| CBMOAB-44070FYA | Mouse Anti-Rhesus GPX2 Antibody (CBMOAB-44070FYA) |
For Research Use Only | Not For Clinical Use.
Online Inquiry