Rabbit Anti-HDAC4 (AA 1000-1084) Antibody (Cat MO-DKB-03155W)


Cat: MO-DKB-03155W
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Size:
Conjugate:
 Inquiry
  • Product Details

Specifications

Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivityHuman (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Primate, Chicken (Gallus gallus), Zebrafish (Danio rerio)
SpecificityThis antibody is binds to Human Histone Deacetylase 4/HDAC4 and has cross reactivity with Mouse, Rat, Primate, Chicken, Zebrafish Histone Deacetylase 4/HDAC4.
ImmunogenA synthetic peptide used in the C-terminal part of the human HDAC4 protein (between residues 1000-1084).
EpitopeAA 1000-1084
FormatLiquid or Lyophilized
BufferPBS
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurificationAffinity purified
Cellular LocalizationNucleus And Cytoplasm.

Application Information

ApplicationWB, IF, IHC, IHC-P
Application NotesWestern Blot: 1.0 ug/mL
Simple Western: 1:100
Immunocytochemistry/Immunofluorescence: 1:500-1:1000
Immunohistochemistry: 1:300
Immunohistochemistry-Paraffin: 1:300
The optimal dilution should be determined by the end user.

Target

IntroductionHistones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.
Product OverviewThis product is a Rabbit antibody against the Histone Deacetylase 4/HDAC4. It can be used for Histone Deacetylase 4/HDAC4 detection in Western Blot, Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin.
Alternative NamesHistone deacetylase; EC 3.5.1.98; hdac
UniProt IDF1QRR4
For Research Use Only | Not For Clinical Use.
Online Inquiry