Mouse Anti-Il2RA Antibody (MOFY-0522-FY39)


Cat: MOFY-0522-FY39
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Specifications

Host speciesMouse
Species ReactivityHuman, Rhesus, Cynomolgus
FormatLiquid or Lyophilized
BufferPBS
Regulatory StatusFor Research Use Only. Not For Clinical Use.
ShippingGel Pack
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use

Application Information

ApplicationFC
Application NotesThe optimal dilution should be determined by the end user.

Target

IntroductionThe interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.
Alternative NamesIL-2-RA; IL-2 receptor subunit alpha; CD25; TCGFR; TAC antigen; IL2R; CD antigen CD25; Interleukin-2 receptor subunit alpha; IL-2R subunit alpha; p55; IL2-RA; IDDM10
Gene ID574300(Rhesus)
UniProt IDQ5MNY4(Rhesus)
For Research Use Only | Not For Clinical Use.
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