Mouse Anti-Mallard HSP60 Antibody (MO-AB-23289H)


Cat: MO-AB-23289H
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityMallard (Anas platyrhynchos)
CloneMO23289C
SpecificityThis antibody binds to Mallard HSP60.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionHsp60 is an abundant, constitutively produced heat shock protein that increases cellular concentration in response to cellular shock. It exists in multiple species and has significant homology in bacteria, plants and mammals. Hsp60 of Plasmodium falciparum is a 577 amino acid polypeptide with a calculated molecular weight of 62158 Da. The primary structure of Plasmodium falciparum hsp60 contains a putative mitochondrial targeting peptide at its amino terminus and a GGM motif at its carboxy terminus. The overall structure shows strong conservation (~50%) for hsp60 in humans and other eukaryotes, but low homology (<30%) with the recently reported P. falciparum chaperone 60 gene. The Plasmodium falciparum hsp60 gene is located on chromosome 10. During heat shock, the levels of hsp60 transcripts increased significantly in blood-stage parasites, and their accumulation correlated with induction duration.
Product OverviewThis product is a mouse antibody against HSP60. It can be used for HSP60 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesHeat shock protein; HSP60
UniProt IDI3QII5
Protein RefseqThe length of the protein is 568 amino acids long.
The sequence is show below: MLRLPAVLRQMRPVSRALAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKAIDLKDKYKNIGARLVQDVANNTNEEAGDGTTTATVLARAIAKEGFEKISKGANPVEIRRGVMLAVDAIIAELKKLSKPVTTPEEIAQVATISANGDQEIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTAKGQKCEFQDAYVLISEKKISSVQSIVPALEIANSHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLNLNVEDIQPHDFGKVGEVIVTKDDTMLLKGKGEKAQIEKRIQEIIEQLEVTTSEYEKEKLNERLAKLSDGVAGTSDVEVNEKKDRVTDALNATRAAVEEGIVPGGGCALLRCIPALDALTPANEDQKIGIEIIKRTLKIPAMTIAKNAGVEGSLIVEKILQSPSEVGYDAMLGDFVNMVEKGIIDPTKVVRTALMDAAGVASLLSTAEAVVTEVPKEEKEPAMGGMGGMGGGMGGGMF.
For Research Use Only | Not For Clinical Use.
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