Rabbit Anti-MsrB1 Antibody (MO-DKB-02225W)


Cat: MO-DKB-02225W
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  • Specifications
  • Application Information
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Specifications

Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivityA. thaliana (Arabidopsis thaliana)
ImmunogenMsrB1 synthetic peptide derived from Arabidopsis AT1G53670.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurityPeptide affinity purified

Application Information

ApplicationWB
Application NotesWestern Blot (1:1000-1:2000) Note: Optimal dilutions/concentrations should be determined by the end user.

Target

IntroductionThe protein encoded by this gene belongs to the methionine-R-sulfoxide reductase B (MsrB) family. Members of this family function as repair enzymes that protect proteins from oxidative stress by catalyzing the reduction of methionine-R-sulfoxides to methionines. This protein is highly expressed in liver and kidney, and is localized to the nucleus and cytosol. It is the only member of the MsrB family that is a selenoprotein, containing a selenocysteine (Sec) residue at its active site. It also has the highest methionine-R-sulfoxide reductase activity compared to other members containing cysteine in place of Sec. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. A pseudogene of this locus has been identified on chromosome 19.
Product OverviewThis product is a Rabbit antibody against the MsrB1. It can be used for MsrB1 detection in Western Blot.
Alternative NamesMethionine Sulfoxide Reductase B1; Selenoprotein X, 1; Selenoprotein R; SEPX1; SELX; Methionine-R-Sulfoxide Reductase B1; Selenoprotein X; MsrB1, ATMSRB1, METHIONINE SULFOXIDE REDUCTASE B 1.
UniProt IDQ9C8M2
For Research Use Only | Not For Clinical Use.
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