Mouse Anti-Nile tilapia HDAC3 Antibody (MO-AB-33287H)
Cat: MO-AB-33287H
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Nile tilapia (Oreochromis niloticus) |
| Clone | MO33287C |
| Specificity | This antibody binds to Nile tilapia HDAC3. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Nucleus |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. |
| Product Overview | This product is a mouse antibody against HDAC3. It can be used for HDAC3 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Histone deacetylase; EC 3.5.1.98; LOC100708372 |
| UniProt ID | I3KFN8 |
| Protein Refseq | The length of the protein is 430 amino acids long. The sequence is show below: MTNRTSYFYDPDVGNFHYGAGHPMKPHRLSLTHSLVLHYGLYKKMMVFKPYKASQHDMCRFHSEDYIDFLQKVSPNNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNHKICDIAINWAGGLHHAKKFEASGFCYVNDIVISILELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYRQLFQPVIKQVVDYYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGFFQLNSNVKSFRIPLLVLGGGGYTVRNVARCWTYETSLLLDESISDELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLEQIRQTVFENLKMLNHAPSVQIHDVPSDMLSYERNDEPDPDERGAEENYTRPEAANEFYDGDHDNDKESDVEI. |
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For Research Use Only | Not For Clinical Use.
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