Rabbit Anti-HDAC3 Antibody (MO-DKB-00716W)


Cat: MO-DKB-00716W
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Specifications

Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivityHuman (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Pig (Sus scrofa), Bovine (Bos taurus), Chicken (Gallus gallus), Rhesus (Macaca mulatta)
ImmunogenA synthetic peptide containing sequences within the C-terminal region of human HDAC3.
EpitopeThe epitope is in the C-terminal of HDAC3.
FormatLiquid or Lyophilized
Buffer0.1M Tris, pH 7, 0.1M Glycine, 10% Glycerol
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurityAffinity purified
Cellular LocalizationNucleus

Application Information

ApplicationWB, ChIP, IF, IHC, IHC-P, IP
Application NotesWestern Blot 1:500-1:3000
Chromatin Immunoprecipitation
Immunocytochemistry/Immunofluorescence 1:100-1:1000
Immunohistochemistry 1:100-1:1000
Immunohistochemistry-Paraffin 1:100-1:1000
Immunoprecipitation 1:1000

Target

IntroductionHistones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008]
Product OverviewThis product is a Rabbit antibody against the C-terminal of the HDAC3. It can be used for HDAC3 detection in Western Blot, Chromatin Immunoprecipitation, Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation.
Alternative NamesHistone Deacetylase 3; EC 3.5.1.98; RPD3-2; SMAP45; HD3; RPD3;
Gene ID8841
UniProt IDO15379
For Research Use Only | Not For Clinical Use.
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