Mouse Anti-O. anatinus ADSL Antibody (MO-AB-06265Y)
Cat: MO-AB-06265Y
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | O. anatinus (Ornithorhynchus anatinus) |
| Clone | MO06265Y |
| Specificity | This antibody binds to O. anatinus ADSL. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Other locations; Cytosol |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | The protein encoded by this gene belongs to the lyase 1 family. It is an essential enzyme involved in purine metabolism, and catalyzes two non-sequential reactions in the de novo purine biosynthetic pathway: the conversion of succinylaminoimidazole carboxamide ribotide (SAICAR) to aminoimidazole carboxamide ribotide (AICAR) and the conversion of adenylosuccinate (S-AMP) to adenosine monophosphate (AMP). Mutations in this gene are associated with adenylosuccinase deficiency (ADSLD), a disorder marked with psychomotor retardation, epilepsy or autistic features. Alternatively spliced transcript variants have been found for this gene. |
| Product Overview | This product is a mouse antibody against ADSL. It can be used for ADSL detection in Western Blot and Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Adenylosuccinate lyase; ASL; EC 4.3.2.2; Adenylosuccinase; ADSL |
| UniProt ID | F7CY55 |
| Protein Refseq | The length of the protein is 420 amino acids long. The sequence is show below: MKSNVDKIDFKTAAKEEKRLRHDVMAHVHTFALCCPKAASIIHLGATSCFVGDNTDLIIFRDAFDLLLPQLARVISRLTDFALKYAQLPTLGFTHFQPAQLTTVGKRCSLWIQDLCMDLENLKRVRDDLRFRGVKGTTGTQASFLQLFEGDHQKVEELERKVAEKAGFKRVFLVTGQTYPRKVDFEVVSVLSSLGASVHKICTDIRLLASLKEIEEPFEKNQIGSSAMAYKRNPMRAERCCSLARHLMTLVMNPLQTASVQWFERTLDDSANRRICLSEAFLAADTVLNTLQNISEGLVVYPKVIERRIRHELPFMATENIIMAMVKAGGNRQDCHEKIRVLSQEAAAVVKQEGGDNDLIVRIRSDPYFSPIHAHLESLLDPSSFTGRAAQQVVTFVKEEVEPLLVPYKDVLNVEAKLEL. |
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For Research Use Only | Not For Clinical Use.
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