Mouse Anti-Cattle ADSL Antibody (MO-AB-07088R)
Cat: MO-AB-07088R
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- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Cattle (Bos taurus) |
Clone | MO07088R |
Specificity | This antibody binds to Cattle ADSL. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Cellular Localization | Cytosol; Other locations |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | The protein encoded by this gene belongs to the lyase 1 family. It is an essential enzyme involved in purine metabolism, and catalyzes two non-sequential reactions in the de novo purine biosynthetic pathway: the conversion of succinylaminoimidazole carboxamide ribotide (SAICAR) to aminoimidazole carboxamide ribotide (AICAR) and the conversion of adenylosuccinate (S-AMP) to adenosine monophosphate (AMP). Mutations in this gene are associated with adenylosuccinase deficiency (ADSLD), a disorder marked with psychomotor retardation, epilepsy or autistic features. Alternatively spliced transcript variants have been found for this gene. |
Product Overview | Mouse Anti-Cattle ADSL Antibody is a mouse antibody against ADSL. It can be used for ADSL detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
Alternative Names | Adenylosuccinate lyase; ASL; EC 4.3.2.2; Adenylosuccinase; ADSL |
UniProt ID | F1MHP6 |
Protein Refseq | The length of the protein is 490 amino acids long. The sequence is show below: MAAAGDRGGREAACGHDSYRSPLASRYASPEMCFLFSDKYKFRTWRQLWLWLAEAEQTLGLPITDEQIQEMKSNLDNIDFRMAAEEEMQLRHDVMAHVHTFAHCCPKAASIIHLGATSCYVGDNTDLIILRNAFDLLLPKLARVISRLADFAKEQADLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDELRFRGVKGTTGTQASFLQLFEGDDQKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDI. |
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For Research Use Only | Not For Clinical Use.
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