Rabbit Anti-PCSK1 (Center) Antibody (Cat MO-DKB-03375W)
Cat: MO-DKB-03375W
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- Product Details
Specifications
| Host species | Rabbit (Oryctolagus cuniculus) |
| Species Reactivity | Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Pig (Sus scrofa), Cattle (Bos taurus), Zebrafish (Danio rerio) |
| Specificity | This antibody is binds to Human Proprotein Convertase 1/PCSK1 and has cross reactivity with Mouse, Rat, Pig, Cattle, Zebrafish Proprotein Convertase 1/PCSK1. |
| Immunogen | Recombinant protein containing sequences in the central region of human PC1/3. |
| Epitope | Center |
| Format | Liquid or Lyophilized |
| Buffer | 0.1 M Tris, pH 7, 0.1 M Glycine, 20% Glycerol |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purification | Affinity purified |
| Cellular Localization | Cytoplasmic Vesicle, Secretory Vesicle |
Application Information
| Application | WB, IHC, IHC-P |
| Application Notes | Western Blot: 1:500-1:3000 Immunohistochemistry: 1:100-1:1000 Immunohistochemistry-Paraffin: 1:100-1:1000 The optimal dilution should be determined by the end user. |
Target
| Introduction | This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to subcellular compartments where a second autocatalytic even takes place and the catalytic activity is acquired. The protease is packaged into and activated in dense core secretory granules and expressed in the neuroendocrine system and brain. This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. It functions in the proteolytic activation of polypeptide hormones and neuropeptides precursors. Mutations in this gene have been associated with susceptibility to obesity and proprotein convertase 1/3 deficiency. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
| Product Overview | This product is a Rabbit antibody against the Proprotein Convertase 1/PCSK1. It can be used for Proprotein Convertase 1/PCSK1 detection in Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin. |
| Alternative Names | Prohormone convertase 1; pcsk |
| UniProt ID | B6VCA1 |
See other products for " PCSK1 "
| MO-AB-37936W | Mouse Anti-Goat PCSK1 Antibody (MO-AB-37936W) |
| MO-AB-16741W | Mouse Anti-Chimpanzee PCSK1 Antibody (MO-AB-16741W) |
| MO-AB-61144W | Mouse Anti-Marmoset PCSK1 Antibody (MO-AB-61144W) |
| MO-AB-17640R | Mouse Anti-Cattle PCSK1 Antibody (MO-AB-17640R) |
| CBMOAB-54056FYA | Mouse Anti-Rhesus PCSK1 Antibody (CBMOAB-54056FYA) |
| MO-AB-28163R | Mouse Anti-Pig PCSK1 Antibody (MO-AB-28163R) |
| CBMOAB-91898FYA | Mouse Anti-Zebrafish pcsk1 Antibody (CBMOAB-91898FYA) |
For Research Use Only | Not For Clinical Use.
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