Rabbit Anti-PEX5 Antibody (MO-DKB-02810W)


Cat: MO-DKB-02810W
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Specifications

Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivityA. thaliana (Arabidopsis thaliana)
ImmunogenA synthetic peptide derived from the PEX5 protein of Arabidopsis AT5G56290.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurityPeptide affinity purified

Application Information

ApplicationWB
Application NotesWestern Blot (1:1000-1:2000) Note: Optimal dilutions/concentrations should be determined by the end user.

Target

IntroductionThe product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified.
Product OverviewThis product is a Rabbit antibody against the PEX5. It can be used for PEX5 detection in Western Blot.
Alternative NamesPeroxisomal Biogenesis Factor 5; Peroxisome Receptor 1; Peroxisomal C-Terminal Targeting Signal Import Receptor; Peroxisomal Targeting Signal 1 Receptor; Peroxisomal Import Receptor 5; PTS1 Receptor; Peroxin-5; PTS1-BP; PTS1R; PEX5, ARABIDOPSIS PEROXIN 5, ATPEX5, EMB2790, EMBRYO DEFECTIVE 2790, PEROXIN 5
UniProt IDQ9FMA3
For Research Use Only | Not For Clinical Use.
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