Cat: MO-AB-23456R
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Pig (Sus scrofa) |
| Clone | MO23456R |
| Specificity | This antibody binds to Pig ABCG8. |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions to exclude non-cholesterol sterol entry at the intestinal level, promote excretion of cholesterol and sterols into bile, and to facilitate transport of sterols back into the intestinal lumen. It is expressed in a tissue-specific manner in the liver, intestine, and gallbladder. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia. |
| Product Overview | This product is a mouse antibody against ABCG8. It can be used for ABCG8 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | ATP-binding cassette sub-family G member 8, Fragment; ABCG8 |
| UniProt ID | A4URS9 |
| Protein Refseq | The length of the protein is 189 amino acids long. The sequence is show below: VRGLTYQVDMASQVPWFEQLAHFKMPWTSHKDSCELGLQNLSFRVRSGQMLAIIGSSGCGRASLLDVITGRGPGGKIKSGQIWINGQPSTPQLVRKYVAHVRQHDQLLPNLTVRETLAFVAQLRLPRTFSQAQRDKRVDDVIAELRLRQCANTRVGNTYIRGVSGGERRRVSIAVQLLWNPGILILDEP. |
See other products for " abcg8 "
| CBMOAB-64433FYA | Mouse Anti-Zebrafish abcg8 Antibody (CBMOAB-64433FYA) |
| CBMOAB-64434FYA | Mouse Anti-Zebrafish abcg8 Antibody (CBMOAB-64434FYA) |
| CBMOAB-64432FYA | Mouse Anti-Zebrafish abcg8 Antibody (CBMOAB-64432FYA) |
| MO-AB-06785R | Mouse Anti-Cattle ABCG8 Antibody (MO-AB-06785R) |
| CBMOAB-1356FYC | Mouse Anti-Arabidopsis ABCG8 Antibody (CBMOAB-1356FYC) |
For Research Use Only | Not For Clinical Use.