Mouse Anti-Pig Cav1 Antibody (MO-AB-24345R)
Cat: MO-AB-24345R
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Pig (Sus scrofa) |
| Clone | MO24345R |
| Specificity | This antibody binds to Pig Cav1. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Plasma membrane; Other locations; Golgi apparatus |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1. May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. |
| Product Overview | This product is a mouse antibody against Cav1. It can be used for Cav1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Caveolin, Fragment; Cav1 |
| UniProt ID | B6VGE2 |
| Protein Refseq | The length of the protein is 113 amino acids long. The sequence is show below: IDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLPSALFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTFCDPLFEAIGKIFSNIRINMQKEI. |
See other products for " CAV1 "
| MO-AB-07450Y | Mouse Anti-Rabbit CAV1 Antibody (MO-AB-07450Y) |
| MO-AB-14467Y | Mouse Anti-Sheep CAV1 Antibody (MO-AB-14467Y) |
| MO-AB-24517H | Mouse Anti-Rat Cav1 Antibody (MO-AB-24517H) |
| MO-AB-43914W | Mouse Anti-Horse CAV1 Antibody (MO-AB-43914W) |
| MOFY-0722-FY419 | Rabbit Anti-CAV1 Antibody (MOFY-0722-FY419) |
| MO-AB-09559R | Mouse Anti-Cattle CAV1 Antibody (MO-AB-09559R) |
| CBMOAB-69148FYA | Mouse Anti-Zebrafish cav1 Antibody (CBMOAB-69148FYA) |
| MO-AB-23012H | Mouse Anti-Mallard CAV1 Antibody (MO-AB-23012H) |
| MO-AB-41348W | Mouse Anti-Guinea pig CAV1 Antibody (MO-AB-41348W) |
| CBMOAB-01096HCB | Mouse Anti-C. elegans CAV1 Antibody (CBMOAB-01096HCB) |
For Research Use Only | Not For Clinical Use.
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