Rabbit Anti-CAV1 Antibody (MOFY-0722-FY419)
Cat: MOFY-0722-FY419
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- Product Details
Specifications
Host species | Rabbit |
Species Reactivity | Goat |
Format | Liquid or Lyophilized |
Buffer | PBS, pH7.4, 50% glycerol |
Regulatory Status | For Research Use Only. Not For Clinical Use. |
Shipping | Gel Pack |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purification | Protein A |
Application Information
Application | WB, IHC, ICC, IP |
Application Notes | WB: 0.5-2 µg/mL IHC: 5-20 µg/mL ICC: 5-20 µg/mL The optimal dilution should be determined by the end user. |
Target
Introduction | The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.[provided by RefSeq, Mar 2010] |
Alternative Names | Caveolin 1; Caveolin 1, Caveolae Protein, 22kDa; Caveolin 1, Caveolae Protein, 22kD; Cell Growth-Inhibiting Protein 32; Caveolin-1; MSTP085; BSCL3; |
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For Research Use Only | Not For Clinical Use.
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