Rabbit Anti-CAV1 Antibody (MOFY-0722-FY126)


Cat: MOFY-0722-FY126
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Specifications

Host speciesRabbit
Species ReactivityRhesus
FormatLiquid or Lyophilized
BufferPBS, pH7.4, 50% glycerol
Regulatory StatusFor Research Use Only. Not For Clinical Use.
ShippingGel Pack
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurificationProtein A

Application Information

ApplicationWB, IHC, ICC, IP
Application NotesWB: 0.5-2 µg/mL
IHC: 5-20 µg/mL
ICC: 5-20 µg/mL
The optimal dilution should be determined by the end user.

Target

IntroductionThe scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.[provided by RefSeq, Mar 2010]
Alternative NamesCaveolin 1; Caveolin 1, Caveolae Protein, 22kDa; Caveolin 1, Caveolae Protein, 22kD; Cell Growth-Inhibiting Protein 32; Caveolin-1; MSTP085; BSCL3;
For Research Use Only | Not For Clinical Use.
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