Mouse Anti-Rad17 Antibody, IgG1 kappa (MOFY-0922-FY28)
Cat: MOFY-0922-FY28
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- Product Details
Specifications
Host species | Mouse |
Species Reactivity | S. pombe |
Clone | M1C6/2 |
Immunogen | Rad17 fusion protein derived from Schizosaccharomyces pombe resistant |
Format | Liquid or Lyophilized |
Buffer | Refer to COA |
Regulatory Status | For Research Use Only. Not For Clinical Use. |
Shipping | Gel Pack |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 95% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Application Information
Application | WB |
Target
Introduction | The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation. The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest, and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells. Multiple alternatively spliced transcript variants of this gene, which encode four distinct protein isoforms, have been reported. Two pseudogenes, located on chromosomes 7 and 13, have been identified. [provided by RefSeq, Jul 2013] |
Product Overview | MOFY-0922-FY28 is a mouse antibody against Rad17. It can be used for Rad17 detection in Western Blot. |
Alternative Names | RAD17 Checkpoint Clamp Loader Component; HRAD17; R24L; Cell Cycle Checkpoint Protein (RAD17); Cell Cycle Checkpoint Protein RAD17; RAD17 Homolog (S. Pombe); RF-C Activator 1 Homolog; RF-C/Activator 1 Homolog |
See other products for " rad17 "
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CBMOAB-55957FYA | Mouse Anti-Rhesus RAD17 Antibody (CBMOAB-55957FYA) |
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MO-AB-62868W | Mouse Anti-Marmoset RAD17 Antibody (MO-AB-62868W) |
MO-AB-06861H | Mouse Anti-Frog Rad17 Antibody (MO-AB-06861H) |
MO-DKB-02493W | Rabbit Anti-RAD17 Antibody (MO-DKB-02493W) |
MO-AB-21057W | Mouse Anti-Chimpanzee RAD17 Antibody (MO-AB-21057W) |
MO-AB-18985R | Mouse Anti-Cattle RAD17 Antibody (MO-AB-18985R) |
CBMOAB-39745FYC | Mouse Anti-Arabidopsis RAD17 Antibody (CBMOAB-39745FYC) |
For Research Use Only | Not For Clinical Use.
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