Mouse Anti-Rhesus CIITA Antibody (CBMOAB-39278FYA)
Cat: CBMOAB-39278FYA
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Size: | |
Conjugate: | |
Inquiry |
- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Rhesus (Macaca mulatta) |
Clone | MO39278FYA |
Specificity | This antibody binds to Rhesus CIITA. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | This gene encodes a protein with an acidic transcriptional activation domain, 4 LRRs (leucine-rich repeats) and a GTP binding domain. The protein is located in the nucleus and acts as a positive regulator of class II major histocompatibility complex gene transcription, and is referred to as the "master control factor" for the expression of these genes. The protein also binds GTP and uses GTP binding to facilitate its own transport into the nucleus. Once in the nucleus it does not bind DNA but rather uses an intrinsic acetyltransferase (AT) activity to act in a coactivator-like fashion. Mutations in this gene have been associated with bare lymphocyte syndrome type II (also known as hereditary MHC class II deficiency or HLA class II-deficient combined immunodeficiency), increased susceptibility to rheumatoid arthritis, multiple sclerosis, and possibly myocardial infarction. Several transcript variants encoding different isoforms have been found for this gene. |
Product Overview | Mouse Anti-Rhesus CIITA Antibody is a mouse antibody against CIITA. It can be used for CIITA detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
Alternative Names | MHC class II transactivator; CIITA |
UniProt ID | H9Z940 |
Protein Refseq | The length of the protein is 1130 amino acids long. The sequence is show below: MRCLAPHPAGSYLSEPQGSSQCATMELGPLEGSYLELLNSDADPLCLYHIYDQMDLAGEEEIELYSEPDTDTINCDQFSRLLCDMEGDEETREAYANIAELDQYVFQDSQLEGLSKDIFKHIGPDEVIGDSMEMPAEVGQKSQKRPFPEELPADLKHWKPAEPPAVVTGSFLVGPVSNSSTLPCLPLPTLFNQEPASGRMRLEETNQMPMPSSSSSLSCLNLPEGPIQFVPTVSTVPQGLWQISGTGTGVSSIFIYHGEVPQASQVPPPSGLTVHGLPTSPDRPGSTSPFAPSATDLPSMPEPALISRANVTEHKTSPTQRQAAGEVSNKLPKWPESVEQFYRSLQDTYRAEPTGPDGILMEVDLVQARLERSSSKSLERELATPDWAERQLAQGGLAEGLLAAKEHRRPRETQVIAMLGKAGQGKSYWAGAVSRAWACGRLPQYDFVFSVPCHCLNRPGDVYRLQDLLFSLGPRPLVAADEVFSHIVKRPDRILLILDAFEELEAQDGFLHSTCGPALAEPCSLRGLLAGLFQKKLLRGCTLLLTARPRGRLVQSLSKADALFELSGFSMEQAQAYVMRYFECSGMTEHQDRALALLRDRPFLLSHSHSPTLCQAVCQLSEALLELGEDAELPSTLTGLYVGLLGRAALNGPPGALAELAKLAWELGRRHQSTLQENQFPSADVRTWAMAKGLVQHPPGATESELAFPSFLLQCFLGALWLALSGEIKDKELPQYLALTPRKKRPYDNWLEGVPRFLTGLIFQPRARCLGALVGPSATAFADRKQKVLARYLKRLQPGTLRARQLLELLHCAHEAEEAGIWQHVVQELPARLSFLGTRLTPPDAHVLGKALEAAGQDFALDLRSTGIDPSGLGSLVGLSCVTHFRAALSDTVALWESLRQHGETELLQAAEEKFTIEPFKAKSLKDVEDLGKLVQTQRTRSSSEDTAGELPAVRDLKKLEFALGPISGPQAFPKLVRILTAFSSLQHLDLDALSENKIGDEGVSQLSATFPQLKSLETLNLSQNSITDLGAYKLAEGLPSLAASLLRLSLYNNCICDMGAESLARVLPDMVSLRVMDVQYNKFTAAGAQQLAASLRKCPHVETLAMWTPTIPFSVQEHLQQQDSRISLR. |
See other products for " CIITA "
MO-AB-24614R | Mouse Anti-Pig CIITA Antibody (MO-AB-24614R) |
CBMOAB-70554FYA | Mouse Anti-Zebrafish ciita Antibody (CBMOAB-70554FYA) |
MO-AB-01211Y | Mouse Anti-Chicken CIITA Antibody (MO-AB-01211Y) |
For Research Use Only | Not For Clinical Use.
Online Inquiry