Mouse Anti-RHO Antibody
Cat: MO-NAB-00459W
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- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Am, Cattle (Bos taurus), Zebrafish (Danio rerio) |
Clone | NW0383 |
Specificity | This antibody is binds to Human RHO and has cross reactivity with Mouse, Rat, Am, Cattle, Zebrafish. |
Immunogen | Bleach the outer section of the ox stem (ROS). |
Format | Liquid or Lyophilized |
Buffer | PBS |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purification | Protein A purified |
Application Information
Application | WB, ELISA, IF, IHC, IP, RIA |
Target
Introduction | Rhodopsin (also called visual purple) is a photosensitive receptor protein involved in visual light transduction. Rhodopsin is a biological pigment found in the rods of the retina, and is a G protein coupled receptor (GPCR). It belongs to opsins. Rhodopsin is extremely sensitive to light, so vision can be achieved in low-light conditions. When rhodopsin is exposed to light, it will bleach immediately. In humans, it fully regenerates in about 30 minutes, after which the rod is more sensitive. The photoactivation product Metarhodopsin II stimulates the G protein transduction protein (Gt) to trigger the visual light transduction pathway, thereby releasing its alpha subunit. This GTP-bound subunit in turn activates cGMP phosphodiesterase. cGMP phosphodiesterase hydrolyzes (decomposes) cGMP, reducing its local concentration, so it can no longer activate cGMP-dependent cation channels. This leads to hyperpolarization of photoreceptor cells, changing the rate at which they release the emitter. |
Product Overview | This product is a Mouse antibody against the RHO. It can be used for RHO detection in Western Blot, Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Radioimmunoassay. |
Alternative Names | RHO; CSNBAD1; OPN2; RP4; rhodopsin; Rhodopsin; visual purple |
Gene ID | 387(Human); 11848(Mouse); 117273(Rat) |
UniProt ID | P61586(Human); Q9QUI0(Mouse); P61589(Rat) |
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For Research Use Only | Not For Clinical Use.
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