Mouse Anti-RHO Antibody


Cat: MO-NAB-00459W
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityHuman (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Am, Cattle (Bos taurus), Zebrafish (Danio rerio)
CloneNW0383
SpecificityThis antibody is binds to Human RHO and has cross reactivity with Mouse, Rat, Am, Cattle, Zebrafish.
ImmunogenBleach the outer section of the ox stem (ROS).
FormatLiquid or Lyophilized
BufferPBS
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurificationProtein A purified

Application Information

ApplicationWB, ELISA, IF, IHC, IP, RIA

Target

IntroductionRhodopsin (also called visual purple) is a photosensitive receptor protein involved in visual light transduction. Rhodopsin is a biological pigment found in the rods of the retina, and is a G protein coupled receptor (GPCR). It belongs to opsins. Rhodopsin is extremely sensitive to light, so vision can be achieved in low-light conditions. When rhodopsin is exposed to light, it will bleach immediately. In humans, it fully regenerates in about 30 minutes, after which the rod is more sensitive. The photoactivation product Metarhodopsin II stimulates the G protein transduction protein (Gt) to trigger the visual light transduction pathway, thereby releasing its alpha subunit. This GTP-bound subunit in turn activates cGMP phosphodiesterase. cGMP phosphodiesterase hydrolyzes (decomposes) cGMP, reducing its local concentration, so it can no longer activate cGMP-dependent cation channels. This leads to hyperpolarization of photoreceptor cells, changing the rate at which they release the emitter.
Product OverviewThis product is a Mouse antibody against the RHO. It can be used for RHO detection in Western Blot, Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Radioimmunoassay.
Alternative NamesRHO; CSNBAD1; OPN2; RP4; rhodopsin; Rhodopsin; visual purple
Gene ID387(Human); 11848(Mouse); 117273(Rat)
UniProt IDP61586(Human); Q9QUI0(Mouse); P61589(Rat)
For Research Use Only | Not For Clinical Use.
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