Mouse Anti-Sheep SQSTM1 Antibody (MO-AB-17785Y)


Cat: MO-AB-17785Y
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivitySheep (Ovis aries)
CloneMO17785Y
SpecificityThis antibody binds to Sheep SQSTM1.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThis gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
Product OverviewThis product is a mouse antibody against SQSTM1. It can be used for SQSTM1 detection in Western Blot and Enzyme-Linked Immunosorbent Assay.
Alternative NamesSequestosome 1; SQSTM1
UniProt IDC5ISA9
Protein RefseqThe length of the protein is 440 amino acids long. The sequence is show below: MASLTVKAYLLGKEDAAREIRRFSFCFSPEPEAEAEAAPGPRPCERLLSRVAALFPVLRPGGFQAHYRDEDGDLVAFSSDEELTMAMSYVKDDIFRIYIKEKKECRRDQRPPCAQEVPRNMVHPNVICDGCNGPVVGTRYKCSVCPDYDLCSACEGKGLHREHGKLAFPSPFGHCSEGFSHSRWLRKLKHGHFGWPGWEMGPPGNWSPRPPQAGEAHPGPATESASGPSEDPSVNFLKNVGESVAAALSPLGIEVDIDVEHGGKRSRLTPSSAGSSSTEEKCSSQPSSCCSDPSKPDRDVEGTTQSLTEQMNKIALESGGQPEEQMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLKEAALYPHLPPEADPRLIESLSQMLSMGFSDEGGWLTRLLQTKNYDIGAALDTIQYSKHPPPL.
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For Research Use Only | Not For Clinical Use.
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