Anti-TNF Antibody (Cat MO-MMB-0670), Mouse IgG1, kappa
Cat: MO-MMB-0670
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- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Dog (Canis lupus familiaris), Cat (Felis catus), Human (Homo sapiens), Mouse (Mus musculus), Rabbit (Oryctolagus cuniculus), Rat (Rattus norvegicus), Zebrafish (Danio rerio) |
Immunogen | Amino acids 115-130 of human protein are used as the immunogen for this anti-TNFα antibody. |
Epitope | N-terminus |
Format | Liquid or Lyophilized |
Buffer | PBS, pH 7.4, 0.1 mg/ml BSA |
Regulatory Status | For Research Use Only |
Shipping | Gel Pack |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purification | Protein G purified |
Application Information
Application | FC, IF, IHC |
Application Notes | FC: 0.5-1 µg/million cells in 0.1 mL IF: 0.5-1 µg/mL IHC: 2-4 µg/mL The optimal dilution should be determined by the end user. |
Target
Introduction | This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq, Jul 2008] |
Alternative Names | Tumor Necrosis Factor; Tumor Necrosis Factor Ligand Superfamily Member 2; Cachectin; TNF-Alpha; TNFSF2; TNF-A; TNFA; Tumor Necrosis Factor (TNF Superfamily, Member 2); Tumor Necrosis Factor Ligand 1F |
Gene ID | 7124 |
UniProt ID | P01375 |
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For Research Use Only | Not For Clinical Use.
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