Mouse Anti-Yeast MUS81 Antibody (CBMOAB-02517CR)


Cat: CBMOAB-02517CR
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityYeast
CloneMO02517CR
SpecificityThis antibody binds to Yeast MUS81.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationNucleus; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionInteracts with MMS4 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks with regressed leading strands and nicked Holliday junctions. Cleavage probably occurs approximately half a helical turn upstream of the free 5'-end in these structures. May be required in mitosis for the processing of stalled replication fork intermediates arising spontaneously or subsequent to treatment with DNA damaging agents such as methylmethane sulfonate (MMS), camptothecin (CPT) or UV. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI). This involves consecutive cleavage of D-loops and nicked Holliday junctions leading to sister chromatid crossover. In contrast to MSH4-MSH5 dependent crossover, double Holliday junctions do not seem to be involved. Spore formation and viability are severely impaired in deletion strains.
Product OverviewMouse Anti-Yeast MUS81 Antibody is a mouse antibody against MUS81. It can be used for MUS81 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesCrossover junction endonuclease MUS81; EC 3.1.22; MMS and UV-sensitive protein 81; MUS81; SLX3; YDR386W
UniProt IDQ04149
Protein RefseqThe length of the protein is 632 amino acids long. The sequence is show below: MELSSNLKDLYIEWLQELVDGLTPKQEQLKIAYEKAKRNLQNAEGSFYYPTDLKKVKGIGNTIIKRLDTKLRNYCKIHHISPVEAPSLTQTSSTRPPKRTTTALRSIVNSCENDKNEAPEEKGTKKRKTRKYIPKKRSGGYAILLSLLELNAIPRGVSKEQIIEVAGKYSDHCMTPNFSTKEFYGAWSSIAALKKHSLVLEEGRPKRYSLTEEGVELTKSLKTADGISFPKENEEPNEYSVTRNESSEFTANLTDLRGEYGKEEEPCDINNTSFMLDITFQDLSTPQRLQNNVFKNDRLNSQTNISSHKLEEVSDDQTVPDSALKAKSTIKRRRYNGVSYELWCSGDFEVFPIIDHREIKSQSDREFFSRAFERKGMKSEIRQLALGDIIWVAKNKNTGLQCVLNTIVERKRLDDLALSIRDNRFMEQKNRLEKSGCEHKYYLIEETMSGNIGNMNEALKTALWVILVYYKFSMIRTCNSDETVEKIHALHTVISHHYSQKDLIVIFPSDLKSKDDYKKVLLQFRREFERKGGIECCHNLECFQELMGKGDLKTVGELTIHVLMLVKGISLEKAVAIQEIFPTLNKILMAYKTCSSEEEAKLLMFNVLGDAPGAKKITKSLSEKIYDAFGKL.
See other products for " MUS81 "
CBMOAB-06922HCBMouse Anti-C. elegans MUS81 Antibody (CBMOAB-06922HCB)
MO-AB-05381HMouse Anti-Frog MUS81 Antibody (MO-AB-05381H)
CBMOAB-25173FYAMouse Anti-D. melanogaster Mus81 Antibody (CBMOAB-25173FYA)
CBMOAB-51954FYAMouse Anti-Rhesus MUS81 Antibody (CBMOAB-51954FYA)
CBMOAB-36821FYCMouse Anti-Arabidopsis MUS81 Antibody (CBMOAB-36821FYC)
CBMOAB-87820FYAMouse Anti-Zebrafish mus81 Antibody (CBMOAB-87820FYA)
MO-AB-10947WMouse Anti-Chimpanzee MUS81 Antibody (MO-AB-10947W)
MO-AB-16238RMouse Anti-Cattle MUS81 Antibody (MO-AB-16238R)
MO-AB-59557WMouse Anti-Marmoset MUS81 Antibody (MO-AB-59557W)
CBMOAB-34761FYBMouse Anti-Rice MUS81 Antibody (CBMOAB-34761FYB)
For Research Use Only | Not For Clinical Use.
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