Caspase 1

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq, Mar 2012]

  • Mouse Anti-Arabidopsis CASP1 Antibody (CBMOAB-25708FYC) (CAT#: CBMOAB-25708FYC)

    • Host species: Mouse
    • Species Reactivity: A. thaliana (Arabidopsis thaliana)
    • Application: WB, ELISA
    • Protein: Casparian strip membrane protein 1
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, None, PE, PerCP
    • Alternative Names: Caspase 1, Caspase 1, Apoptosis-Related Cysteine Peptidase, Interleukin 1, Beta, Convertase, IL-1 Beta-Converting Enzyme, EC 3.4.22.36, Caspase-1, IL1BC, P45, ICE, Caspase 1, Apoptosis-Related Cysteine Peptidase (Interleukin 1, Beta, Convertase), Caspase 1, Apoptosis-Related Cysteine Protease (Interleukin 1, Beta, Convertase)

  • Mouse Anti-Rhesus CASP1 Antibody (CBMOAB-38172FYA) (CAT#: CBMOAB-38172FYA)

    • Host species: Mouse
    • Species Reactivity: Rhesus (Macaca mulatta)
    • Application: WB, ELISA
    • Protein: Submitted name: Caspase-1 isoform alpha
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Caspase-1 isoform alpha, CASP1

  • Mouse Anti-Rabbit CASP1 Antibody (MO-AB-07437Y) (CAT#: MO-AB-07437Y)

    • Host species: Mouse
    • Species Reactivity: Rabbit (Oryctolagus cuniculus)
    • Application: WB, ELISA
    • Protein: Submitted name: Caspase 1
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Caspase, CASP1

  • Mouse Anti-Cat CASP1 Antibody (MO-AB-07849W) (CAT#: MO-AB-07849W)

    • Host species: Mouse
    • Species Reactivity: Cat (Felis catus)
    • Application: WB, ELISA
    • Protein: Caspase-1
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Caspase-1, CASP-1, EC 3.4.22.36, Interleukin-1 beta convertase, IL-1BC, Interleukin-1 beta-converting enzyme, ICE, IL-1 beta-converting enzyme, p45, [Cleaved into: Caspase-1 subunit p20, Caspase-1 subunit p10], CASP1, IL1BC

  • Mouse Anti-Chimpanzee CASP1 Antibody (MO-AB-11410W) (CAT#: MO-AB-11410W)

    • Host species: Mouse
    • Species Reactivity: Chimpanzee (Pan troglodytes)
    • Application: WB, ELISA
    • Protein: Submitted name: Caspase 1
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Caspase, CASP1

  • Mouse Anti-Pig CASP1 Antibody (MO-AB-24307R) (CAT#: MO-AB-24307R)

    • Host species: Mouse
    • Species Reactivity: Pig (Sus scrofa)
    • Application: WB, ELISA
    • Protein: Submitted name: Caspase-1
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Caspase, CASP1

  • Mouse Anti-Dog CASP1 Antibody (MO-AB-29332W) (CAT#: MO-AB-29332W)

    • Host species: Mouse
    • Species Reactivity: Dog (Canis lupus familiaris)
    • Application: WB, ELISA
    • Protein: Caspase-1
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Caspase-1, CASP-1, EC 3.4.22.36, Interleukin-1 beta convertase, IL-1BC, Interleukin-1 beta-converting enzyme, ICE, IL-1 beta-converting enzyme, p45, [Cleaved into: Caspase-1 subunit p20, Caspase-1 subunit p10], CASP1, IL1BC

  • Mouse Anti-Horse CASP1 Antibody (MO-AB-43905W) (CAT#: MO-AB-43905W)

    • Host species: Mouse
    • Species Reactivity: Horse (Equus caballus)
    • Application: WB, ELISA
    • Protein: Caspase-1
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Caspase-1, CASP-1, EC 3.4.22.36, Interleukin-1 beta convertase, IL-1BC, Interleukin-1 beta-converting enzyme, ICE, IL-1 beta-converting enzyme, p45, [Cleaved into: Caspase-1 subunit p20, Caspase-1 subunit p10], CASP1, IL1BC

  • Rabbit Anti-CASP1 Antibody (MO-DKB-00555W) (CAT#: MO-DKB-00555W)

    • Host species: Rabbit
    • Species Reactivity: Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), E. coli (Escherichia coli)
    • Application: WB, IF, IHC, IHC-P, IP, KD
    • Protein: Caspase-1
    • Size: 100µg
    • Conjugate: NONE
    • Alternative Names: Caspase 1, Caspase 1, Apoptosis-Related Cysteine Peptidase, Interleukin 1, Beta, Convertase, IL-1 Beta-Converting Enzyme, EC 3.4.22.36, Caspase-1, IL1BC, P45, ICE, Caspase 1, Apoptosis-Related Cysteine Peptidase (Interleukin 1, Beta, Convertase), Caspase 1, Apoptosis-Related Cysteine Protease (Interleukin 1, Beta, Convertase)

  • Rabbit Anti-CASP1 Antibody (MOFAB-003W) (CAT#: MOFAB-003W)

    • Host species: Rabbit
    • Species Reactivity: Zebrafish
    • Application: ELISA, WB, IP
    • Protein: Caspase 1
    • Size: 100µL
    • Conjugate: None
    • Alternative Names: Caspase 1, Caspase 1, Apoptosis-Related Cysteine Peptidase, Interleukin 1, Beta, Convertase, IL-1 Beta-Converting Enzyme, EC 3.4.22.36, Caspase-1, IL1BC, P45, ICE, Caspase 1, Apoptosis-Related Cysteine Peptidase (Interleukin 1, Beta, Convertase), Caspase 1, Apoptosis-Related Cysteine Protease (Interleukin 1, Beta, Convertase), Caspase-1

  • Rabbit Anti-CASP1 Antibody (MOFY-0722-FY281) (CAT#: MOFY-0722-FY281)

    • Host species: Rabbit
    • Species Reactivity: Pig, Human
    • Application: WB, IHC, ICC, IP
    • Protein: Caspase 1
    • Size: 100µL
    • Conjugate: None
    • Alternative Names: Caspase 1, Caspase 1, Apoptosis-Related Cysteine Peptidase, Interleukin 1, Beta, Convertase, IL-1 Beta-Converting Enzyme, EC 3.4.22.36, Caspase-1, IL1BC, P45, ICE, Caspase 1, Apoptosis-Related Cysteine Peptidase (Interleukin 1, Beta, Convertase), Caspase 1, Apoptosis-Related Cysteine Protease (Interleukin 1, Beta, Convertase)

  • Mouse Anti-Cattle Casp1 Antibody (MO-AB-09510R) (CAT#: MO-AB-09510R)

    • Host species: Mouse
    • Species Reactivity: Cattle (Bos taurus)
    • Application: WB, ELISA
    • Protein: Submitted name: Caspase-1
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Caspase-1, Fragment, Casp1
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