Mouse Anti-Cattle Casp1 Antibody (MO-AB-09510R)
Cat: MO-AB-09510R
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- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Cattle (Bos taurus) |
Clone | MO09510R |
Specificity | This antibody binds to Cattle Casp1. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq, Mar 2012] |
Product Overview | Mouse Anti-Cattle Casp1 Antibody is a mouse antibody against Casp1. It can be used for Casp1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
Alternative Names | Caspase-1, Fragment; Casp1 |
UniProt ID | A0PCH9 |
Protein Refseq | The length of the protein is 389 amino acids long. The sequence is show below: EKRKLFVHSVSKGTINGLLDELLEKRVLNQEEMEKIRDENDTAMDRARVLIDTVIRKGPQACQICISHICEEDSHLAGILGLTSGSQSENYLRQKPQAVVPPFPAPQAMLDNPVKLASSGPGGNLKLCPPETAQRIRKEKSGEIYPIMERSNRTRLALIICNTEFENLTRRDGADVDTRNMKVLLEGLGYKVDVKENLTASEMILELKAFAAHSEHRTSDSTFLVFMSHGIRAGICGKKYSEEVPDILKVDDIFH. |
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For Research Use Only | Not For Clinical Use.
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