Rabbit Anti-CASP1 Antibody (MO-DKB-00555W)
Cat: MO-DKB-00555W
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- Product Details
Specifications
| Host species | Rabbit (Oryctolagus cuniculus) |
| Species Reactivity | Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), E. coli (Escherichia coli) |
| Immunogen | A synthetic peptide around amino acid 132 of human caspase-1. |
| Format | Liquid or Lyophilized |
| Buffer | PBS, pH 7.2, 0.5 mM EDTA, 0.5% BSA, 30% glycerol |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | Affinity purified |
Application Information
| Application | WB, IF, IHC, IHC-P, IP, KD |
| Application Notes | Western Blot 0.5-4 ug/ml Immunocytochemistry/Immunofluorescence 10-20 ug/ml Immunohistochemistry Immunohistochemistry-Paraffin Immunoprecipitation 4-8 ug/ml |
Target
| Introduction | This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq, Mar 2012] |
| Product Overview | This product is a Rabbit antibody against the CASP1. It can be used for CASP1 detection in Western Blot, Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Knockdown Validated. |
| Alternative Names | Caspase 1; Caspase 1, Apoptosis-Related Cysteine Peptidase; Interleukin 1, Beta, Convertase; IL-1 Beta-Converting Enzyme; EC 3.4.22.36; Caspase-1; IL1BC; P45; ICE; Caspase 1, Apoptosis-Related Cysteine Peptidase (Interleukin 1, Beta, Convertase); Caspase 1, Apoptosis-Related Cysteine Protease (Interleukin 1, Beta, Convertase); |
| Gene ID | 834 |
| UniProt ID | P29466 |
See other products for " CASP1 "
| MO-AB-07849W | Mouse Anti-Cat CASP1 Antibody (MO-AB-07849W) |
| MO-AB-24307R | Mouse Anti-Pig CASP1 Antibody (MO-AB-24307R) |
| CBMOAB-38172FYA | Mouse Anti-Rhesus CASP1 Antibody (CBMOAB-38172FYA) |
| MO-AB-09510R | Mouse Anti-Cattle Casp1 Antibody (MO-AB-09510R) |
| MO-AB-11410W | Mouse Anti-Chimpanzee CASP1 Antibody (MO-AB-11410W) |
| CBMOAB-25708FYC | Mouse Anti-Arabidopsis CASP1 Antibody (CBMOAB-25708FYC) |
| MO-AB-43905W | Mouse Anti-Horse CASP1 Antibody (MO-AB-43905W) |
| MOFY-0722-FY281 | Rabbit Anti-CASP1 Antibody (MOFY-0722-FY281) |
| MO-AB-07437Y | Mouse Anti-Rabbit CASP1 Antibody (MO-AB-07437Y) |
| MOFAB-003W | Rabbit Anti-CASP1 Antibody (MOFAB-003W) |
For Research Use Only | Not For Clinical Use.
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