Cbl Proto-Oncogene

This gene is a proto-oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates. This protein also contains an N-terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine-phosphorylated substrates and target them for proteasome degradation. As such it functions as a negative regulator of many signal transduction pathways. This gene has been found to be mutated or translocated in many cancers including acute myeloid leukaemia, and expansion of CGG repeats in the 5' UTR has been associated with Jacobsen syndrome. Mutations in this gene are also the cause of Noonan syndrome-like disorder. [provided by RefSeq, Jul 2016]

  • Mouse Anti-Arabidopsis CBL Antibody (CBMOAB-25772FYC) (CAT#: CBMOAB-25772FYC)

    • Host species: Mouse
    • Species Reactivity: A. thaliana (Arabidopsis thaliana)
    • Application: WB, ELISA
    • Protein: Submitted name: Cystathionine beta-lyase
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, None, PE, PerCP
    • Alternative Names: Cbl Proto-Oncogene, Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence, Cbl Proto-Oncogene, E3 Ubiquitin Protein Ligase, Casitas B-Lineage Lymphoma Proto-Oncogene, RING-Type E3 Ubiquitin Transferase CBL, Signal Transduction Protein CBL, RING Finger Protein 55, Proto-Oncogene C-Cbl, Oncogene CBL2, RNF55
  • Mouse Anti-Arabidopsis CBL Antibody (MO-AB-00333H) (CAT#: MO-AB-00333H)

    • Host species: Mouse
    • Species Reactivity: Arabidopsis (Arabidopsis lyrata)
    • Application: WB, ELISA
    • Protein: Submitted name: Cystathionine beta-lyase
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Cystathionine beta-lyase, CBL
  • Mouse Anti-Chimpanzee CBL Antibody (MO-AB-12174W) (CAT#: MO-AB-12174W)

    • Host species: Mouse
    • Species Reactivity: Chimpanzee (Pan troglodytes)
    • Application: WB, ELISA
    • Protein: E3 ubiquitin-protein ligase CBL
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Cas-Br-M (Murine) ecotropic retroviral transforming sequence, CBL
  • Mouse Anti-Marmoset CBL Antibody (MO-AB-52306W) (CAT#: MO-AB-52306W)

    • Host species: Mouse
    • Species Reactivity: Marmoset
    • Application: WB, ELISA
    • Protein: E3 ubiquitin-protein ligase CBL
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: E3 ubiquitin-protein ligase CBL, CBL
  • Rabbit Anti-CBL Antibody (MO-DKB-01359W) (CAT#: MO-DKB-01359W)

    • Host species: Rabbit
    • Species Reactivity: Human (Homo sapiens), Rhesus (Macaca mulatta)
    • Application: WB, IF
    • Protein: E3 ubiquitin-protein ligase CBL
    • Size: 100µL
    • Conjugate: NONE
    • Alternative Names: Cbl Proto-Oncogene, Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence, Cbl Proto-Oncogene, E3 Ubiquitin Protein Ligase, Casitas B-Lineage Lymphoma Proto-Oncogene, RING-Type E3 Ubiquitin Transferase CBL, Signal Transduction Protein CBL, RING Finger Protein 55, Proto-Oncogene C-Cbl, Oncogene CBL2, RNF55
  • Mouse Anti-E. coli cbl Antibody (CBMOAB-0315YC) (CAT#: CBMOAB-0315YC)

    • Host species: Mouse
    • Species Reactivity: E. coli (Escherichia coli )
    • Application: WB, ELISA
    • Protein: HTH-type transcriptional regulator cbl
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, None, PE, PerCP
    • Alternative Names: HTH-type transcriptional regulator cbl, cbl, b1987 JW1966
  • Mouse Anti-Zebrafish cbl Antibody (CBMOAB-69164FYA) (CAT#: CBMOAB-69164FYA)

    • Host species: Mouse
    • Species Reactivity: Zebrafish (Danio rerio)
    • Application: WB, ELISA
    • Protein: E3 ubiquitin-protein ligase CBL
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: cbl, Cbl Proto-Oncogene
  • Mouse Anti-Frog Cbl Antibody (MO-AB-02112H) (CAT#: MO-AB-02112H)

    • Host species: Mouse
    • Species Reactivity: Frog (Xenopus laevis)
    • Application: WB, ELISA
    • Protein: E3 ubiquitin-protein ligase CBL
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Cbl proto-oncogene protein, Cbl
  • Mouse Anti-Fruit fly Cbl Antibody (MO-AB-02332W) (CAT#: MO-AB-02332W)

    • Host species: Mouse
    • Species Reactivity: Fruit fly (Drosophila melanogaster)
    • Application: WB, ELISA
    • Protein: E3 ubiquitin-protein ligase CBL
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: CG7037-PB, isoform B, Cbl long isoform, Cbl
  • Mouse Anti-Tomato cbl Antibody (MO-AB-34246H) (CAT#: MO-AB-34246H)

    • Host species: Mouse
    • Species Reactivity: Tomato (Lycopersicon esculentum)
    • Application: WB, ELISA
    • Protein: Submitted name: Calcineurin B-like molecule
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Calcineurin B-like molecule, Calcium sensor calcineurin B-like protein, cbl, SlSOS3
  • Mouse Anti-Drosophila Cbl Antibody (Full length) (CAT#: MO-NAB-00758W)

    • Host species: Mouse
    • Species Reactivity: D. melanogaster (Drosophila melanogaster)
    • Application: IF, WB
    • Protein: E3 ubiquitin-protein ligase CBL
    • Size: 1mL
    • Conjugate: NONE
    • Alternative Names: D-cbl protein, Cbl
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