Glutathione Peroxidase 4

The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of hydrogen peroxide, organic hydroperoxides and lipid hydroperoxides, and thereby protect cells against oxidative damage. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme has a high preference for lipid hydroperoxides and protects cells against membrane lipid peroxidation and cell death. It is also required for normal sperm development; thus, it has been identified as a 'moonlighting' protein because of its ability to serve dual functions as a peroxidase, as well as a structural protein in mature spermatozoa. Mutations in this gene are associated with Sedaghatian type of spondylometaphyseal dysplasia (SMDS). This isozyme is also a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene.

  • Rabbit Anti-Mouse GPX4 Antibody (CBMOAB-00314FYA) (CAT#: CBMOAB-00314FYA)

    • Host species: Rabbit
    • Species Reactivity: Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Zebrafish (Danio rerio)
    • Application: WB, IHC
    • Protein: Phospholipid hydroperoxide glutathione peroxidase
    • Size: 100µg, 50µg
    • Conjugate: None
    • Alternative Names: Glutathione Peroxidase 4, Phospholipid Hydroperoxidase, EC 1.11.1.12, GSHPx-4, GPx-4, PHGPx, Phospholipid Hydroperoxide Glutathione Peroxidase, Mitochondrial, Glutathione Peroxidase 4 (Phospholipid Hydroperoxidase)
  • Mouse Anti-C. elegans GPX4 Antibody (CBMOAB-04658HCB) (CAT#: CBMOAB-04658HCB)

    • Host species: Mouse
    • Species Reactivity: C. elegans (Caenorhabditis elegans)
    • Application: WB, ELISA
    • Protein: Glutathione peroxidase
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Glutathione peroxidase, gpx-4
  • Mouse Anti-Arabidopsis GPX4 Antibody (CBMOAB-34191FYC) (CAT#: CBMOAB-34191FYC)

    • Host species: Mouse
    • Species Reactivity: A. thaliana (Arabidopsis thaliana)
    • Application: WB, ELISA
    • Protein: Probable glutathione peroxidase 4
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, None, PE, PerCP
    • Alternative Names: Glutathione Peroxidase 4, Phospholipid Hydroperoxidase, EC 1.11.1.12, GSHPx-4, GPx-4, PHGPx, Phospholipid Hydroperoxide Glutathione Peroxidase, Mitochondrial, Glutathione Peroxidase 4 (Phospholipid Hydroperoxidase)
  • Mouse Anti-Rhesus GPX4 Antibody (CBMOAB-44072FYA) (CAT#: CBMOAB-44072FYA)

    • Host species: Mouse
    • Species Reactivity: Rhesus (Macaca mulatta)
    • Application: WB, ELISA
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: GPX4
  • Mouse Anti-Rhesus GPX4 Antibody (CBMOAB-60124FYC) (CAT#: CBMOAB-60124FYC)

    • Host species: Mouse
    • Species Reactivity: Rhesus (Macaca mulatta)
    • Application: WB, ELISA
    • Protein: Submitted name: Phospholipid hydroperoxide glutathione peroxidase, mitochondrial isoform C
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Phospholipid hydroperoxide glutathione peroxidase, mitochondrial isoform C, GPX4
  • Mouse Anti-Chicken GPX4 Antibody (MO-AB-02216Y) (CAT#: MO-AB-02216Y)

    • Host species: Mouse
    • Species Reactivity: Chicken (Gallus gallus)
    • Application: WB, ELISA
    • Protein: Glutathione peroxidase
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Glutathione peroxidase, GPX4
  • Mouse Anti-Cat GPX4 Antibody (MO-AB-07695W) (CAT#: MO-AB-07695W)

    • Host species: Mouse
    • Species Reactivity: Cat (Felis catus)
    • Application: WB, ELISA
    • Protein: Glutathione peroxidase
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Glutathione peroxidase, GPX4
  • Mouse Anti-Cattle GPX4 Antibody (MO-AB-13333R) (CAT#: MO-AB-13333R)

    • Host species: Mouse
    • Species Reactivity: Cattle (Bos taurus)
    • Application: WB, ELISA
    • Protein: Phospholipid hydroperoxide glutathione peroxidase
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Phospholipid hydroperoxide glutathione peroxidase, mitochondrial, PHGPx, EC 1.11.1.12, Glutathione peroxidase 4, GPx-4, GSHPx-4, GPX4
  • Mouse Anti-Chimpanzee GPX4 Antibody (MO-AB-18189W) (CAT#: MO-AB-18189W)

    • Host species: Mouse
    • Species Reactivity: Chimpanzee (Pan troglodytes)
    • Application: WB, ELISA
    • Protein: Glutathione peroxidase
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Glutathione peroxidase, GPX4
  • Rabbit Anti-GPX4 Antibody (MO-DKB-01994W) (CAT#: MO-DKB-01994W)

    • Host species: Rabbit
    • Species Reactivity: A. thaliana (Arabidopsis thaliana)
    • Application: WB
    • Protein: Probable glutathione peroxidase 4
    • Size: 150µg
    • Conjugate: NONE
    • Alternative Names: Glutathione Peroxidase 4, Phospholipid Hydroperoxidase, EC 1.11.1.12, GSHPx-4, GPx-4, PHGPx, Phospholipid Hydroperoxide Glutathione Peroxidase, Mitochondrial, Glutathione Peroxidase 4 (Phospholipid Hydroperoxidase), GPX4, ATGPX4, GLUTATHIONE PEROXIDASE 4, GPXL4.
  • Rabbit Anti-GPX4 Antibody (AA 30-70) (CAT#: MO-NAB-00372W)

    • Host species: Rabbit
    • Species Reactivity: Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Zebrafish (Danio rerio)
    • Application: WB, IHC, IHC-P
    • Protein: Phospholipid hydroperoxide glutathione peroxidase; Phospholipid hydroperoxide glutathione peroxidase; Phospholipid hydroperoxide glutathione peroxidase
    • Size: 100µg
    • Conjugate: NONE
    • Alternative Names: Glutathione Peroxidase 4, Phospholipid Hydroperoxidase, EC 1.11.1.12, GSHPx-4, GPx-4, PHGPx, Phospholipid Hydroperoxide Glutathione Peroxidase, Mitochondrial, Glutathione Peroxidase 4 (Phospholipid Hydroperoxidase)
  • Mouse Anti-Frog gpx4 Antibody (MO-AB-04046H) (CAT#: MO-AB-04046H)

    • Host species: Mouse
    • Species Reactivity: Frog (Xenopus laevis)
    • Application: WB, ELISA
    • Protein: Submitted name: LOC100036920 protein
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: LOC100036920 protein, gpx4, LOC100036920
  • Mouse Anti-Rat Gpx4 Antibody (MO-AB-26106H) (CAT#: MO-AB-26106H)

    • Host species: Mouse
    • Species Reactivity: Rat (Rattus norvegicus)
    • Application: WB, ELISA
    • Protein: Phospholipid hydroperoxide glutathione peroxidase
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Phospholipid hydroperoxide glutathione peroxidase, nuclear, EC 1.11.1.12, Glutathione peroxidase 4, GPx-4, GSHPx-4, Gpx4
  • Mouse Anti-Goat GPx4 Antibody (MO-AB-37382W) (CAT#: MO-AB-37382W)

    • Host species: Mouse
    • Species Reactivity: Goat (Capra hircus)
    • Application: WB, ELISA
    • Protein: Glutathione peroxidase
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Glutathione peroxidase, GPx4
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