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Glutathione Peroxidase 4

The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of hydrogen peroxide, organic hydroperoxides and lipid hydroperoxides, and thereby protect cells against oxidative damage. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme has a high preference for lipid hydroperoxides and protects cells against membrane lipid peroxidation and cell death. It is also required for normal sperm development; thus, it has been identified as a 'moonlighting' protein because of its ability to serve dual functions as a peroxidase, as well as a structural protein in mature spermatozoa. Mutations in this gene are associated with Sedaghatian type of spondylometaphyseal dysplasia (SMDS). This isozyme is also a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene.

Cat# Product Name Host species Species Reactivity Application Size Conjugate Alternative Names Protein
CBMOAB-00314FYA Rabbit Anti-Mouse GPX4 Antibody (CBMOAB-00314FYA) Rabbit Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Zebrafish (Danio rerio) WB, IHC 100µg, 50µg None Glutathione Peroxidase 4, Phospholipid Hydroperoxidase, EC 1.11.1.12, GSHPx-4, GPx-4, PHGPx, Phospholipid Hydroperoxide Glutathione Peroxidase, Mitochondrial, Glutathione Peroxidase 4 (Phospholipid Hydroperoxidase) Phospholipid hydroperoxide glutathione peroxidase
CBMOAB-04658HCB Mouse Anti-C. elegans GPX4 Antibody (CBMOAB-04658HCB) Mouse C. elegans (Caenorhabditis elegans) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP Glutathione peroxidase, gpx-4 Glutathione peroxidase
CBMOAB-34191FYC Mouse Anti-Arabidopsis GPX4 Antibody (CBMOAB-34191FYC) Mouse A. thaliana (Arabidopsis thaliana) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, None, PE, PerCP Glutathione Peroxidase 4, Phospholipid Hydroperoxidase, EC 1.11.1.12, GSHPx-4, GPx-4, PHGPx, Phospholipid Hydroperoxide Glutathione Peroxidase, Mitochondrial, Glutathione Peroxidase 4 (Phospholipid Hydroperoxidase) Probable glutathione peroxidase 4
CBMOAB-44072FYA Mouse Anti-Rhesus GPX4 Antibody (CBMOAB-44072FYA) Mouse Rhesus (Macaca mulatta) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP GPX4
CBMOAB-60123FYC Mouse Anti-Rhesus GPX4 Antibody (CBMOAB-60123FYC) Mouse Rhesus (Macaca mulatta) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP Phospholipid hydroperoxide glutathione peroxidase, mitochondrial isoform A, GPX4 Submitted name: Phospholipid hydroperoxide glutathione peroxidase, mitochondrial isoform A
CBMOAB-60124FYC Mouse Anti-Rhesus GPX4 Antibody (CBMOAB-60124FYC) Mouse Rhesus (Macaca mulatta) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP Phospholipid hydroperoxide glutathione peroxidase, mitochondrial isoform C, GPX4 Submitted name: Phospholipid hydroperoxide glutathione peroxidase, mitochondrial isoform C
MO-AB-02216Y Mouse Anti-Chicken GPX4 Antibody (MO-AB-02216Y) Mouse Chicken (Gallus gallus) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP Glutathione peroxidase, GPX4 Glutathione peroxidase
MO-AB-07695W Mouse Anti-Cat GPX4 Antibody (MO-AB-07695W) Mouse Cat (Felis catus) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP Glutathione peroxidase, GPX4 Glutathione peroxidase
MO-AB-13333R Mouse Anti-Cattle GPX4 Antibody (MO-AB-13333R) Mouse Cattle (Bos taurus) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP Phospholipid hydroperoxide glutathione peroxidase, mitochondrial, PHGPx, EC 1.11.1.12, Glutathione peroxidase 4, GPx-4, GSHPx-4, GPX4 Phospholipid hydroperoxide glutathione peroxidase
MO-AB-18189W Mouse Anti-Chimpanzee GPX4 Antibody (MO-AB-18189W) Mouse Chimpanzee (Pan troglodytes) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP Glutathione peroxidase, GPX4 Glutathione peroxidase
MO-DKB-01994W Rabbit Anti-GPX4 Antibody (MO-DKB-01994W) Rabbit A. thaliana (Arabidopsis thaliana) WB 150µg NONE Glutathione Peroxidase 4, Phospholipid Hydroperoxidase, EC 1.11.1.12, GSHPx-4, GPx-4, PHGPx, Phospholipid Hydroperoxide Glutathione Peroxidase, Mitochondrial, Glutathione Peroxidase 4 (Phospholipid Hydroperoxidase), GPX4, ATGPX4, GLUTATHIONE PEROXIDASE 4, GPXL4. Probable glutathione peroxidase 4
MO-NAB-00372W Rabbit Anti-GPX4 Antibody (AA 30-70) Rabbit Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Zebrafish (Danio rerio) WB, IHC, IHC-P 100µg NONE Glutathione Peroxidase 4, Phospholipid Hydroperoxidase, EC 1.11.1.12, GSHPx-4, GPx-4, PHGPx, Phospholipid Hydroperoxide Glutathione Peroxidase, Mitochondrial, Glutathione Peroxidase 4 (Phospholipid Hydroperoxidase) Phospholipid hydroperoxide glutathione peroxidase; Phospholipid hydroperoxide glutathione peroxidase; Phospholipid hydroperoxide glutathione peroxidase
MO-AB-04046H Mouse Anti-Frog gpx4 Antibody (MO-AB-04046H) Mouse Frog (Xenopus laevis) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP LOC100036920 protein, gpx4, LOC100036920 Submitted name: LOC100036920 protein
MO-AB-04047H Mouse Anti-Frog gpx4 Antibody (MO-AB-04047H) Mouse Frog (Xenopus laevis) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP MGC130849 protein, MGC130849 Submitted name: MGC130849 protein
MO-AB-26103H Mouse Anti-Rat Gpx4 Antibody (MO-AB-26103H) Mouse Rat (Rattus norvegicus) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP Glutathione peroxidase, Gpx4 Glutathione peroxidase
MO-AB-26104H Mouse Anti-Rat Gpx4 Antibody (MO-AB-26104H) Mouse Rat (Rattus norvegicus) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP Phospholipid hydroperoxide glutathione peroxidase, mitochondrial, PHGPx, EC 1.11.1.12, Glutathione peroxidase 4, GPx-4, GSHPx-4, Gpx4 Phospholipid hydroperoxide glutathione peroxidase
MO-AB-26105H Mouse Anti-Rat Gpx4 Antibody (MO-AB-26105H) Mouse Rat (Rattus norvegicus) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP Glutathione peroxidase, Gpx4 Phospholipid hydroperoxide glutathione peroxidase
MO-AB-26106H Mouse Anti-Rat Gpx4 Antibody (MO-AB-26106H) Mouse Rat (Rattus norvegicus) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP Phospholipid hydroperoxide glutathione peroxidase, nuclear, EC 1.11.1.12, Glutathione peroxidase 4, GPx-4, GSHPx-4, Gpx4 Phospholipid hydroperoxide glutathione peroxidase
MO-AB-37382W Mouse Anti-Goat GPx4 Antibody (MO-AB-37382W) Mouse Goat (Capra hircus) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP Glutathione peroxidase, GPx4 Glutathione peroxidase
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