Mouse Anti-GPX4 Antibody (CBMOAB-04658HCB)
Cat: CBMOAB-04658HCB
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
- Product List
- Specifications
- Application Information
- Target
| Sub Cat | Clonality | Species Reactivity | Application | Clone | Conjugate | Size | |
| CBMOAB-04658HCB | Monoclonal | C. elegans (Caenorhabditis elegans), Cat (Felis catus), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Zebrafish (Danio rerio), Rhesus (Macaca mulatta) | WB, ELISA | MO04658HB | 100 µg | ||
| CBMOAB-00314FYA | Monoclonal | Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Zebrafish (Danio rerio) | WB, IHC | F00314FYA | 100 µg | ||
| CBMOAB-44072FYA | Monoclonal | Rhesus (Macaca mulatta) | WB, ELISA | MO44072FYA | 100 µg | ||
| CBMOAB-60124FYC | Monoclonal | Rhesus (Macaca mulatta) | WB, ELISA | MO60124FYC | 100 µg | ||
| MO-AB-07695W | Monoclonal | Cat (Felis catus) | WB, ELISA | MO07695W | 100 µg | ||
| MO-AB-18189W | Monoclonal | Chimpanzee (Pan troglodytes) | WB, ELISA | MO18189W | 100 µg | ||
| MO-AB-13333R | Monoclonal | Cattle (Bos taurus) | WB, ELISA | MO13333R | 100 µg | ||
| MO-AB-04046H | Monoclonal | Frog (Xenopus laevis) | WB, ELISA | MO04046C | 100 µg | ||
| MO-AB-26106H | Monoclonal | Rat (Rattus norvegicus) | WB, ELISA | MO26106C | 100 µg | ||
| MO-NAB-00372W | Monoclonal | Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Zebrafish (Danio rerio) | WB, IHC, IHC-P | NW0297 | 100 µg |
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | C. elegans (Caenorhabditis elegans), Cat (Felis catus), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Zebrafish (Danio rerio), Rhesus (Macaca mulatta) |
| Clone | MO04658HB |
| Specificity | This antibody binds to C. elegans GPX4. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Extracellular region or secreted |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of hydrogen peroxide, organic hydroperoxides and lipid hydroperoxides, and thereby protect cells against oxidative damage. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme has a high preference for lipid hydroperoxides and protects cells against membrane lipid peroxidation and cell death. It is also required for normal sperm development; thus, it has been identified as a 'moonlighting' protein because of its ability to serve dual functions as a peroxidase, as well as a structural protein in mature spermatozoa. Mutations in this gene are associated with Sedaghatian type of spondylometaphyseal dysplasia (SMDS). This isozyme is also a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene. |
| Product Overview | Mouse Anti-C. elegans GPX4 Antibody is a mouse antibody against GPX4. It can be used for GPX4 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Glutathione peroxidase; gpx-4 |
| UniProt ID | Q9N2X2 |
| Protein Refseq | The length of the protein is 126 amino acids long. The sequence is show below: MASNSLLTLAVSFTVILFAFCVEVDDTLRWKQCAVTNQSVFDFQIETLKGDYTDLSQYRGKVTLLVNVATFCAYTQQYTDFNPILDKYQKQGLVIAAFPCNQFYLQEPAENHELLNGLTHVRPGNG. |
See other products for " GPX4 "
| MO-DKB-01994W | Rabbit Anti-GPX4 Antibody (MO-DKB-01994W) |
| MO-AB-37382W | Mouse Anti-GPx4 Antibody (MO-AB-37382W) |
| CBMOAB-34191FYC | Mouse Anti-GPX4 Antibody (CBMOAB-34191FYC) |
| MO-AB-02216Y | Mouse Anti-GPX4 Antibody (MO-AB-02216Y) |
For Research Use Only | Not For Clinical Use.
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