Methyl-CpG-binding domain protein 2
DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. The protein encoded by this gene may function as a mediator of the biological consequences of the methylation signal. It is also reported that the this protein functions as a demethylase to activate transcription, as DNA methylation causes gene silencing. Two transcript variants encoding different isoforms have been found for this gene.
Mouse Anti-C. elegans MBD2 Antibody (CBMOAB-06416HCB) (CAT#: CBMOAB-06416HCB)
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- Host species: Mouse
- Species Reactivity: C. elegans (Caenorhabditis elegans)
- Application: WB, ELISA
- Protein: Submitted name: MBD_C domain-containing protein
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Methyl-binding protein-2, Protein MBD-2, mbd-2
Mouse Anti-Arabidopsis MBD2 Antibody (CBMOAB-36272FYC) (CAT#: CBMOAB-36272FYC)
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- Host species: Mouse
- Species Reactivity: A. thaliana (Arabidopsis thaliana)
- Application: WB, ELISA
- Protein: Methyl-CpG-binding domain-containing protein 2
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, None, PE, PerCP
- Alternative Names: Methyl-CpG Binding Domain Protein 2, Demethylase, DMTase, Methyl-CpG-Binding Domain Protein 2, Methyl-CpG-Binding Protein MBD2, NY-CO-41
Mouse Anti-Rhesus MBD2 Antibody (CBMOAB-50937FYA) (CAT#: CBMOAB-50937FYA)
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- Host species: Mouse
- Species Reactivity: Rhesus (Macaca mulatta)
- Application: WB, ELISA
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: MBD2
Mouse Anti-Chicken MBD2 Antibody (MO-AB-02829Y) (CAT#: MO-AB-02829Y)
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- Host species: Mouse
- Species Reactivity: Chicken (Gallus gallus)
- Application: WB, ELISA
- Protein: Submitted name: Methyl-CpG-binding domain protein 2
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Methyl-CpG-binding domain protein 2, MBD2
Mouse Anti-Rhesus MBD2 Antibody (MO-AB-04315W) (CAT#: MO-AB-04315W)
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- Host species: Mouse
- Species Reactivity: Rhesus (Macaca mulatta)
- Application: WB, ELISA
- Protein: Submitted name: Methyl-CpG-binding domain protein 2 isoform 1
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Methyl-CpG-binding domain protein 2 isoform 1, MBD2
Mouse Anti-Zebrafish mbd2 Antibody (CBMOAB-86157FYA) (CAT#: CBMOAB-86157FYA)
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- Host species: Mouse
- Species Reactivity: Zebrafish (Danio rerio)
- Application: WB, ELISA
- Protein: Submitted name: Mbd2 protein
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Mbd2 protein, Methyl-CpG binding domain protein 2, Methyl-CpG binding protein 2, mbd
Mouse Anti-Frog mbd2 Antibody (MO-AB-05060H) (CAT#: MO-AB-05060H)
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- Host species: Mouse
- Species Reactivity: Frog (Xenopus laevis)
- Application: WB, ELISA
- Protein: Submitted name: Methyl-CpG binding protein MBD2
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Methyl-CpG binding protein MBD2, mbd2, MBD2
