Niemann-Pick type C1 disease protein
This gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain. It is predicted to have a cytoplasmic C-terminus, 13 transmembrane domains, and 3 large loops in the lumen of the endosome - the last loop being at the N-terminus. This protein transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolized and released as free cholesterol. Defects in this gene cause Niemann-Pick type C disease, a rare autosomal recessive neurodegenerative disorder characterized by over accumulation of cholesterol and glycosphingolipids in late endosomal/lysosomal compartments.
Mouse Anti-Arabidopsis NPC1 Antibody (CBMOAB-37463FYC) (CAT#: CBMOAB-37463FYC)
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- Host species: Mouse
- Species Reactivity: A. thaliana (Arabidopsis thaliana)
- Application: WB, ELISA
- Protein: Non-specific phospholipase C1
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, None, PE, PerCP
- Alternative Names: NPC Intracellular Cholesterol Transporter 1, Niemann-Pick Disease, Type C1, Truncated Niemann-Pick C1, Niemann-Pick C1 Protein, SLC65A1, NPC
Mouse Anti-Rhesus NPC1 Antibody (CBMOAB-52879FYA) (CAT#: CBMOAB-52879FYA)
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- Host species: Mouse
- Species Reactivity: Rhesus (Macaca mulatta)
- Application: WB, ELISA
- Protein: Submitted name: NPC intracellular cholesterol transporter 1
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: NPC1
Mouse Anti-Rabbit NPC1 Antibody (MO-AB-08976Y) (CAT#: MO-AB-08976Y)
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- Host species: Mouse
- Species Reactivity: Rabbit (Oryctolagus cuniculus)
- Application: WB, ELISA
- Protein: Submitted name: NPC intracellular cholesterol transporter 1
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Niemann-Pick type C1 disease protein, NPC1
Mouse Anti-Cat NPC1 Antibody (MO-AB-09206W) (CAT#: MO-AB-09206W)
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- Host species: Mouse
- Species Reactivity: Cat (Felis catus)
- Application: WB, ELISA
- Protein: Submitted name: Niemann-Pick type C1 disease protein
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Niemann-Pick type C1 disease protein, NPC1
Mouse Anti-Cattle NPC1 Antibody (MO-AB-16871R) (CAT#: MO-AB-16871R)
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- Host species: Mouse
- Species Reactivity: Cattle (Bos taurus)
- Application: WB, ELISA
- Protein: Submitted name: Niemann-Pick type C1 disease protein
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Niemann-Pick type C1 disease protein, NPC1
Mouse Anti-Chimpanzee NPC1 Antibody (MO-AB-18745W) (CAT#: MO-AB-18745W)
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- Host species: Mouse
- Species Reactivity: Chimpanzee (Pan troglodytes)
- Application: WB, ELISA
- Protein: Submitted name: Niemann-Pick disease, type C1
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Niemann-Pick disease, type C1, NPC1
Mouse Anti-Pig NPC1 Antibody (MO-AB-27810R) (CAT#: MO-AB-27810R)
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- Host species: Mouse
- Species Reactivity: Pig (Sus scrofa)
- Application: WB, ELISA
- Protein: Submitted name: NPC intracellular cholesterol transporter 1
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Niemann-Pick C1 protein, NPC1
Mouse Anti-Dog NPC1 Antibody (MO-AB-32200W) (CAT#: MO-AB-32200W)
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- Host species: Mouse
- Species Reactivity: Dog (Canis lupus familiaris)
- Application: WB, ELISA
- Protein: Submitted name: Niemann-Pick type C1 disease protein
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Niemann-Pick type C1 disease protein, NPC1
Mouse Anti-Hamsters NPC1 Antibody (MO-AB-43314W) (CAT#: MO-AB-43314W)
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- Host species: Mouse
- Species Reactivity: Hamsters (Cricetinae)
- Application: WB, ELISA
- Protein: Submitted name: Niemann-Pick type C1 protein
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Niemann-Pick type C1 protein, NPC1
Mouse Anti-Marmoset NPC1 Antibody (MO-AB-60245W) (CAT#: MO-AB-60245W)
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- Host species: Mouse
- Species Reactivity: Marmoset
- Application: WB, ELISA
- Protein: Submitted name: Niemann-Pick C1 protein
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Niemann-Pick C1 protein, NPC1
Mouse Anti-Zebrafish npc1 Antibody (CBMOAB-89707FYA) (CAT#: CBMOAB-89707FYA)
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- Host species: Mouse
- Species Reactivity: Zebrafish (Danio rerio)
- Application: WB, ELISA
- Protein: Submitted name: Niemann-Pick disease type C1 protein
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Niemann-Pick disease type C1 protein, npc1, NPC
For Research Use Only | Not For Clinical Use.
