Rabbit Anti-BDNF Antibody (C-terminal)


Cat: MO-NAB-00428W
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Specifications

Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivityHuman (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Zebrafish (Danio rerio)
CloneNW0353
SpecificityThis antibody is binds to Human BDNF and has cross reactivity with Mouse, Rat, Zebrafish.
ImmunogenSynthetic peptide within the C-terminal human BDNF.
EpitopeThe epitope is in the C-terminal of BDNF.
FormatLiquid
BufferTBS, pH7.4, 1% BSA, 40% Glycerol.
StorageStore at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PurificationProtein A purified
Cellular LocalizationSecreted

Application Information

ApplicationWB, IF, IHC, IHC-P
Application NotesWestern Blot: 1:1000-1:2000
Immunofluorescence: 1:50-1:200
Immunohistochemistry-Paraffin: 1:50-1:200

Target

IntroductionThis gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders.
Product OverviewThis product is a Rabbit antibody against the C-terminal of the BDNF. It can be used for BDNF detection in Western Blot, Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin.
Alternative NamesBrain Derived Neurotrophic Factor; Neurotrophin; Abrineurin; Brain-Derived Neurotrophic Factor; ANON2; BULN2
Gene ID627 (Human); 12064 (Mouse); 24225 (Rat)
UniProt IDP23560 (Human); P21237 (Mouse); P23363 (Rat)
For Research Use Only | Not For Clinical Use.

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