Mouse Anti-Cattle CD247 Antibody (MO-AB-09801R)
Cat: MO-AB-09801R
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Cattle (Bos taurus) |
| Clone | MO09801R |
| Specificity | This antibody binds to Cattle CD247. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Plasma membrane; Other locations |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of downstream signaling pathways. CD3Z ITAMs phosphorylation creates multiple docking sites for the protein kinase ZAP70 leading to ZAP70 phosphorylation and its conversion into a catalytically active enzyme. Plays an important role in intrathymic T-cell differentiation. Additionally, participates in the activity-dependent synapse formation of retinal ganglion cells (RGCs) in both the retina and dorsal lateral geniculate nucleus (dLGN). |
| Product Overview | Mouse Anti-Cattle CD247 Antibody is a mouse antibody against CD247. It can be used for CD247 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | CD247 molecule; CD247 |
| UniProt ID | Q0VCU4 |
| Protein Refseq | The length of the protein is 166 amino acids long. The sequence is show below: MKWTALVIVAILQAQFPITAAQSFGLLDPKLCYLLDGILFIYGVIVTALFLRAKFSRSANAPAYQQGQNPVYNELNVGRREEYAVLDRRGGFDPEKGGKPQRKKNPNEVVYNELRKDKMAEAYSEIGMKSDNQRRRGKGHDGLYQGLSTATKDTYDALHMQALPPR. |
See other products for " Cd247 "
| MO-AB-24621H | Mouse Anti-Rat Cd247 Antibody (MO-AB-24621H) |
| MO-AB-14493Y | Mouse Anti-Sheep CD247 Antibody (MO-AB-14493Y) |
| MO-AB-01557W | Mouse Anti-Rhesus CD247 Antibody (MO-AB-01557W) |
| MO-AB-07520Y | Mouse Anti-Rabbit CD247 Antibody (MO-AB-07520Y) |
| MO-AB-34515W | Mouse Anti-Ferret CD247 Antibody (MO-AB-34515W) |
| MO-AB-02199H | Mouse Anti-Frog cd247 Antibody (MO-AB-02199H) |
| CBMOAB-38678FYA | Mouse Anti-Rhesus CD247 Antibody (CBMOAB-38678FYA) |
| CBMOAB-69668FYA | Mouse Anti-Zebrafish cd247 Antibody (CBMOAB-69668FYA) |
For Research Use Only | Not For Clinical Use.
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