Mouse Anti-Cattle MLH1 Antibody (MO-AB-15835R)


Cat: MO-AB-15835R
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityCattle (Bos taurus)
CloneMO15835R
SpecificityThis antibody binds to Cattle MLH1.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionRequired for DNA mismatch repair (MMR), correcting base-base mismatches and insertion-deletion loops (IDLs) resulting from DNA replication, DNA damage or from recombination events between non-identical sequences during meiosis. Component of different MutL heterodimers that form a ternary complex with the MutS heterodimers, which initially recognize the DNA mismatches. This complex is thought to be responsible for directing the downsteam MMR events, including strand discrimination, excision, and resynthesis. Plays a major role in maintaining the genetic stability of simple sequence repeats, the repair of heteroduplex sites present in meiotic recombination intermediates, and the promotion of meiotic crossing-over.
Product OverviewMouse Anti-Cattle MLH1 Antibody is a mouse antibody against MLH1. It can be used for MLH1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesMutL homolog 1, colon cancer, nonpolyposis type 2; E. coli; MLH1
UniProt IDQ1RMN2
Protein RefseqThe length of the protein is 233 amino acids long.
The sequence is show below: MLHNHSFVGCVNPQWALAQHQTKLYLLNTTRLSEELFYQILVYDFANFGVLRLSEPAPLFDLAMLALDSPESGWTEEDGPKEGLAEYIVEFLKKKAEMLADYFSLEIDEEGNLVGLPLLIDNYVPPLEGLPIFILRLATEVNWDEEKECFESLSKECAMFYSIRKQYVSAESTLSGQQSEVPGSTANPWKWTVEHVIYKAFRSHLLPPKHFTEDGNILQLANLPDLYKVFERC.
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For Research Use Only | Not For Clinical Use.
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