Mouse Anti-Pig MLH1 Antibody (MO-AB-27317R)
Cat: MO-AB-27317R
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Pig (Sus scrofa) |
| Clone | MO27317R |
| Specificity | This antibody binds to Pig MLH1. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | Required for DNA mismatch repair (MMR), correcting base-base mismatches and insertion-deletion loops (IDLs) resulting from DNA replication, DNA damage or from recombination events between non-identical sequences during meiosis. Component of different MutL heterodimers that form a ternary complex with the MutS heterodimers, which initially recognize the DNA mismatches. This complex is thought to be responsible for directing the downsteam MMR events, including strand discrimination, excision, and resynthesis. Plays a major role in maintaining the genetic stability of simple sequence repeats, the repair of heteroduplex sites present in meiotic recombination intermediates, and the promotion of meiotic crossing-over. |
| Product Overview | This product is a mouse antibody against MLH1. It can be used for MLH1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | MutL-like protein 1; MLH1 |
| UniProt ID | D3K5L8 |
| Protein Refseq | The length of the protein is 757 amino acids long. The sequence is show below: MSQVPGVIRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAKSTSIQVVVKEGGLKLIQIQDNGTGIRKEDLDIVCERFTTSKLQSFEDLAHISTYGFRGEALASISHVAHVAITTKTADGKCAYRAHYSDGKLKAPPKPCAGNQGTQITVEDLFYNISTRRKALKNPSEEYGKILEVVGRYSIHNSGISFSVKKQGETVADVRTLPNATTVDNIRSIFGNAVSRELIEVECEDKTLAFKMNGYISNANYSVKKCIFLLFINHRLVESTSLRKAIETVYAAYLPKNTHPFLYLSLEISPQNVDVNVHPTKHEVHFLHEDSILERVQQHIESRLLGSNASRTYFTQTLLPGLTGPSGEAVKSAADVTPSSTGSGDKVYAYQMVRTDCREQKLDAFLQPASKSLSSQPQAIVPEDRTDAFGSEARQQDEEMLELPAPSEVAAKHQSLEEDTAERTSDLSEKRGPPSSPGNPRKRHRESSDVEMVEDANRKEMTAACIPRRRIINLTSVLTLQEEINERGHETLREMLHNHSFVGCVNPQWALAQHQTKLYLLNTTKLSEELFYQILIYDFANFGVLRLSEPAPLFDLAMLALDSPESGWTEEDGPKEGLAEYIVEFLKKKAEMLADYFSLEIDEEGNLVGLPLLIDNYVPPLEGLPIFILRLATEVNWDEEKECFESLSKECAMFYSIRKQYISEESTLSGQQSEAPGSTPNPWKWTVEHVVYKAFRSYLLPPKCFTEDGNILQLANLPDLYKVFERC. |
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| MO-AB-05207H | Mouse Anti-Frog mlh1 Antibody (MO-AB-05207H) |
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| CBMOAB-87041FYA | Mouse Anti-Zebrafish mlh1 Antibody (CBMOAB-87041FYA) |
| CBMOAB-36558FYC | Mouse Anti-Arabidopsis MLH1 Antibody (CBMOAB-36558FYC) |
For Research Use Only | Not For Clinical Use.
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