Mouse Anti-Cattle UMOD Antibody (MO-AB-22598R)
Cat: MO-AB-22598R
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- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Cattle (Bos taurus) |
Clone | MO22598R |
Specificity | This antibody binds to Cattle UMOD. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Cellular Localization | Plasma membrane; Extracellular region or secreted; Cytoskeleton; Other locations |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | The protein encoded by this gene is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of this protein in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the renal disorders medullary cystic kidney disease-2 (MCKD2), glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI), and familial juvenile hyperuricemic nephropathy (FJHN). Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
Product Overview | This product is a mouse antibody against UMOD. It can be used for UMOD detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
Alternative Names | Uromodulin; Tamm-Horsfall urinary glycoprotein; THP; [Cleaved into: Uromodulin, secreted form]; UMOD |
UniProt ID | P48733 |
Protein Refseq | The length of the protein is 643 amino acids long. The sequence is show below: MKCLFSPNFMWMAAVVTSWVIIPAATDTSSAKSCSECHSNATCTVDGAATTCACQEGFTGDGLECVDLDECAVLGAHNCSATKSCVNTLGSYTCVCPEGFLLSSELGCEDVDECAEPGLSRCHALATCINGEGNYSCVCPAGYLGDGRHCECSPGSCGPGLDCVREGDALVCVDPCQVHRILDEYWRSTEYGSGYICDVSLGGWYRFVGQAGVRLPETCVPVLHCNTAAPMWLNGTHPSSDEGIVNRVACAHWSG. |
See other products for " UMOD "
MO-AB-33932W | Mouse Anti-Dog UMOD Antibody (MO-AB-33932W) |
MOFY-0722-FY208 | Rabbit Anti-UMOD Antibody (MOFY-0722-FY208) |
CBMOAB-61841FYA | Mouse Anti-Rhesus UMOD Antibody (CBMOAB-61841FYA) |
For Research Use Only | Not For Clinical Use.
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