Rabbit Anti-UMOD Antibody (MOFY-0722-FY208)
Cat: MOFY-0722-FY208
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- Product Details
Specifications
Host species | Rabbit |
Species Reactivity | Dog, Human, Mouse |
Immunogen | Recombinant Uromodulin (UMOD) |
Format | Liquid or Lyophilized |
Buffer | PBS, pH7.4, 50% glycerol |
Regulatory Status | For Research Use Only. Not For Clinical Use. |
Shipping | Gel Pack |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purification | Protein A |
Application Information
Application | WB, IHC, ICC, IP |
Application Notes | WB: 0.5-2 µg/mL ICC: 5-20 µg/mL IHC: 5-20 µg/mL IHC: 5-20 µg/mL ELISA: 0.05-2 µg/mL The optimal dilution should be determined by the end user. |
Target
Introduction | The protein encoded by this gene is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of this protein in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the renal disorders medullary cystic kidney disease-2 (MCKD2), glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI), and familial juvenile hyperuricemic nephropathy (FJHN). Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
Alternative Names | Uromodulin; Tamm-Horsfall Urinary Glycoprotein; Uromucoid; THP; Uromodulin (Uromucoid, Tamm-Horsfall Glycoprotein); Tamm-Horsfall Glycoprotein; ADMCKD2; |
Gene ID | 7369 |
UniProt ID | P07911 |
See other products for " UMOD "
MO-AB-22598R | Mouse Anti-Cattle UMOD Antibody (MO-AB-22598R) |
CBMOAB-61841FYA | Mouse Anti-Rhesus UMOD Antibody (CBMOAB-61841FYA) |
MO-AB-33932W | Mouse Anti-Dog UMOD Antibody (MO-AB-33932W) |
For Research Use Only | Not For Clinical Use.
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