Rabbit Anti-UMOD Antibody (MOFY-0722-FY208)

Cat: MOFY-0722-FY208
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  • Product Details


Host speciesRabbit
Species ReactivityDog, Human, Mouse
ImmunogenRecombinant Uromodulin (UMOD)
FormatLiquid or Lyophilized
BufferPBS, pH7.4, 50% glycerol
Regulatory StatusFor Research Use Only. Not For Clinical Use.
ShippingGel Pack
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurificationProtein A

Application Information

ApplicationWB, IHC, ICC, IP
Application NotesWB: 0.5-2 µg/mL
ICC: 5-20 µg/mL
IHC: 5-20 µg/mL
IHC: 5-20 µg/mL
ELISA: 0.05-2 µg/mL
The optimal dilution should be determined by the end user.


IntroductionThe protein encoded by this gene is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of this protein in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the renal disorders medullary cystic kidney disease-2 (MCKD2), glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI), and familial juvenile hyperuricemic nephropathy (FJHN). Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Alternative NamesUromodulin; Tamm-Horsfall Urinary Glycoprotein; Uromucoid; THP; Uromodulin (Uromucoid, Tamm-Horsfall Glycoprotein); Tamm-Horsfall Glycoprotein; ADMCKD2;
Gene ID7369
UniProt IDP07911
For Research Use Only | Not For Clinical Use.
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