Mouse Anti-Chicken CD8A Antibody (MO-AB-01078Y)


Cat: MO-AB-01078Y
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityChicken (Gallus gallus)
CloneMO01078Y
SpecificityThis antibody binds to Chicken CD8A.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationPlasma membrane

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionCD8A (CD8a Molecule) is a Protein Coding gene. Diseases associated with CD8A include Cd8 Deficiency, Familial and Primary Cutaneous Aggressive Epidermotropic Cd8+ T-Cell Lymphoma. Among its related pathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and T-Cell Receptor and Co-stimulatory Signaling. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and coreceptor activity.
Product OverviewThis product is a mouse antibody against CD8A. It can be used for CD8A detection in Western Blot and Enzyme-Linked Immunosorbent Assay.
Alternative NamesCD8 alpha chain; CD8A
UniProt IDQ0R4I4
Protein RefseqThe length of the protein is 235 amino acids long. The sequence is show below: MAGSPALLLLLSLGLCCTGAQGQRNTMEARFLNRNMKHPQEGQRLELECMPFNIDNGVSWIRQDKDGKLHFIVYISPLSRTAFPRNERTSSQFEGSKQGSSFRLVVKNFRAQDQGTYFCIANINQMLYFSSGQPAFFPATTTAAPTTAAATTQSSHVNKDICMPSSEPGTSGENILNLYCEIFIWAPLAGVCLVLLVALIVTIVLCQKTRRRRCRCKRPPNGKPGAKPCVPTRHI.

Reference

Reference1. Luhtala, M., Tregaskes, C. A., Young, J. R., & Vainio, O. (1997). Polymorphism of chicken CD8-alpha, but not CD8-beta. Immunogenetics, 46, 396-401.
2. Luhtala, M., Koskinen, R., Toivanen, P., & Vainio, O. (1995). Characterization of chicken CD8-specific monoclonal antibodies recognizing novel epitopes. Scandinavian journal of immunology, 42(1), 171-174.
3. Tregaskes, C. A., Kong, F. K., Paramithiotis, E., Chen, C. L., Ratcliffe, M. J., Davison, T. F., & Young, J. R. (1995). Identification and analysis of the expression of CD8 alpha beta and CD8 alpha alpha isoforms in chickens reveals a major TCR-gamma delta CD8 alpha beta subset of intestinal intraepithelial lymphocytes. Journal of immunology (Baltimore, Md.: 1950), 154(9), 4485-4494.
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For Research Use Only | Not For Clinical Use.
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