Mouse Anti-CIAPIN1 Antibody (MO-AB-07585Y)


Cat: MO-AB-07585Y
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Lot Number

  • Product List
  • Specifications
  • Application Information
  • Target
Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
MO-AB-07585Y Monoclonal Rabbit (Oryctolagus cuniculus), Cat (Felis catus), Cattle (Bos taurus), Dog (Canis lupus familiaris), Ferret (Mustela Putorius Furo), Hamsters (Cricetinae), Horse (Equus caballus), Marmoset, O. mykiss (Oncorhynchus mykiss), Rhesus (Macaca mulatta), Sheep (Ovis aries), Zebrafish (Danio rerio) WB, ELISA MO07585Y 100 µg
CBMOAB-39265FYA Monoclonal Rhesus (Macaca mulatta) WB, ELISA MO39265FYA 100 µg
CBMOAB-70535FYA Monoclonal Zebrafish (Danio rerio) WB, ELISA MO70535FYA 100 µg
MO-AB-07860W Monoclonal Cat (Felis catus) WB, ELISA MO07860W 100 µg
MO-AB-29552W Monoclonal Dog (Canis lupus familiaris) WB, ELISA MO29552W 100 µg
MO-AB-34563W Monoclonal Ferret (Mustela Putorius Furo) WB, ELISA MO34563W 100 µg
MO-AB-43012W Monoclonal Hamsters (Cricetinae) WB, ELISA MO43012W 100 µg
MO-AB-44052W Monoclonal Horse (Equus caballus) WB, ELISA MO44052W 100 µg
MO-AB-53028W Monoclonal Marmoset WB, ELISA MO53028W 100 µg
MO-AB-10243R Monoclonal Cattle (Bos taurus) WB, ELISA MO10243R 100 µg
MO-AB-10906Y Monoclonal O. mykiss (Oncorhynchus mykiss) WB, ELISA MO10906Y 100 µg
MO-AB-14567Y Monoclonal Sheep (Ovis aries) WB, ELISA MO14567Y 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityRabbit (Oryctolagus cuniculus), Cat (Felis catus), Cattle (Bos taurus), Dog (Canis lupus familiaris), Ferret (Mustela Putorius Furo), Hamsters (Cricetinae), Horse (Equus caballus), Marmoset, O. mykiss (Oncorhynchus mykiss), Rhesus (Macaca mulatta), Sheep (Ovis aries), Zebrafish (Danio rerio)
CloneMO07585Y
SpecificityThis antibody binds to Rabbit CIAPIN1.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationOther locations; Mitochondrion

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionCIAPIN1 is a cytokine-induced inhibitor of apoptosis with no relation to apoptosis regulatory molecules of the BCL2 or CASP families. Expression of CIAPIN1 is dependent on growth factor stimulation. Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit. Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells.
Product OverviewThis product is a mouse antibody against CIAPIN1. It can be used for CIAPIN1 detection in Western Blot and Enzyme-Linked Immunosorbent Assay.
Alternative NamesAnamorsin; Cytokine-induced apoptosis inhibitor 1; Fe-S cluster assembly protein DRE2 homolog; CIAPIN1
UniProt IDG1ST58
Protein RefseqThe length of the protein is 314 amino acids long. The sequence is show below: MAEFGISAGQAVAVVWDKSSPVEALKELVDKLHVLTGSEGQVSVENVNQLLQSAHKESSFDVILSGVVPGSSMLHSAEVLAEMARILRPGGCLFLKEPVETAVVNNGKVRTASKLCSALTLSGLVEVKELQRESLSPEETQCVQEHLGYTSDGLLSVQITGKKPDFEVGSSSQLRLSSTKKPSPGDSAKPAVDPAVAKLWTLSANDMDDESTDLIDSDELLDAEDLKKPDPASLRAASCGEGKKRKACKNCTCGLAEELEKEKSVQQKSSQPKSACGNCYLGDAFRCASCPYLGMPAFKPGEKVLLSASNLHDA.
For Research Use Only | Not For Clinical Use.
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