Rabbit Anti-D. melanogaster Ago1 (AA 1-100, clone NW0010) Antibody (MOMUB-00013W)


Cat: MOMUB-00013W
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Specifications

Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivityFruit fly (Drosophila melanogaster)
CloneNW0010
ImmunogenA synthetic peptide corresponding to Drosophila Ago1 aa 1-100, which binds to keyhole limpet hemocyanin.
EpitopeAA 1-100
FormatLiquid or Lyophilized
BufferPBS, 50% glycerol
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurificationImmunogen affinity purified
Cellular LocalizationCytoplasm> P-body.

Application Information

ApplicationWB
Application NotesWB: 1 µg/ml

Target

IntroductionThis gene encodes a member of the argonaute family of proteins, which associate with small RNAs and have important roles in RNA interference (RNAi) and RNA silencing. This protein binds to microRNAs (miRNAs) or small interfering RNAs (siRNAs) and represses translation of mRNAs that are complementary to them. It is also involved in transcriptional gene silencing (TGS) of promoter regions that are complementary to bound short antigene RNAs (agRNAs), as well as in the degradation of miRNA-bound mRNA targets. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study showed this gene to be an authentic stop codon readthrough target, and that its mRNA could give rise to an additional C-terminally extended isoform by use of an alternative in-frame translation termination codon. [provided by RefSeq, Nov 2015]
Product OverviewRabbit Anti-D. melanogaster Ago1 (AA 1-100, clone NW0010) Antibody (MOMUB-00013W) is a Rabbit antibody against the epitope (AA 1-100 ) of theAgo1. It can be used for Ago1 detection in Western Blot.
Alternative NamesArgonaute 1, RISC Catalytic Component; Argonaute RISC Catalytic Component 1; Eukaryotic Translation Initiation Factor 2C, 1; Putative RNA-Binding Protein Q99; Argonaute1; EIF-2C 1; EIF2C 1; EIF2C1; HAgo1
For Research Use Only | Not For Clinical Use.
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