Rabbit Anti-D. melanogaster Ago1 (AA 1-100, clone NW0010) Antibody (MOMUB-00013W)
Cat: MOMUB-00013W
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Specifications
Host species | Rabbit (Oryctolagus cuniculus) |
Species Reactivity | Fruit fly (Drosophila melanogaster) |
Clone | NW0010 |
Immunogen | A synthetic peptide corresponding to Drosophila Ago1 aa 1-100, which binds to keyhole limpet hemocyanin. |
Epitope | AA 1-100 |
Format | Liquid or Lyophilized |
Buffer | PBS, 50% glycerol |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purification | Immunogen affinity purified |
Cellular Localization | Cytoplasm> P-body. |
Application Information
Application | WB |
Application Notes | WB: 1 µg/ml |
Target
Introduction | This gene encodes a member of the argonaute family of proteins, which associate with small RNAs and have important roles in RNA interference (RNAi) and RNA silencing. This protein binds to microRNAs (miRNAs) or small interfering RNAs (siRNAs) and represses translation of mRNAs that are complementary to them. It is also involved in transcriptional gene silencing (TGS) of promoter regions that are complementary to bound short antigene RNAs (agRNAs), as well as in the degradation of miRNA-bound mRNA targets. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study showed this gene to be an authentic stop codon readthrough target, and that its mRNA could give rise to an additional C-terminally extended isoform by use of an alternative in-frame translation termination codon. [provided by RefSeq, Nov 2015] |
Product Overview | Rabbit Anti-D. melanogaster Ago1 (AA 1-100, clone NW0010) Antibody (MOMUB-00013W) is a Rabbit antibody against the epitope (AA 1-100 ) of theAgo1. It can be used for Ago1 detection in Western Blot. |
Alternative Names | Argonaute 1, RISC Catalytic Component; Argonaute RISC Catalytic Component 1; Eukaryotic Translation Initiation Factor 2C, 1; Putative RNA-Binding Protein Q99; Argonaute1; EIF-2C 1; EIF2C 1; EIF2C1; HAgo1 |
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For Research Use Only | Not For Clinical Use.
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