Mouse Anti-Elephant EIF3F Antibody (MO-AB-00416L)


Cat: MO-AB-00416L
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityElephant (Loxodonta africana)
CloneMO00416L
SpecificityThis antibody binds to Elephant EIF3F.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionComponent of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
Product OverviewThis product is a mouse antibody against EIF3F. It can be used for EIF3F detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesEukaryotic Translation Initiation Factor 3 Subunit F; Eukaryotic Translation Initiation Factor 3, Subunit 5 Epsilon, 47kDa; Deubiquitinating Enzyme EIF3f; EIF-3-Epsilon; EIF3S5; Eukaryotic Translation Initiation Factor 3, Subunit 5 (Epsilon, 47kD); Eukaryotic Translation Initiation Factor 3, Subunit F
UniProt IDG3U0S6
Protein RefseqThe length of the protein is 369 amino acids long. The sequence is show below: MATPPSPTSTPPATPSPAPATEPAPAPAPAPSPAAAPAPAPAPASAPVPAPASAPASSSDPASAAATTSASAQSSASVQAPAQTSAPPPPGPALPGPFPGGRVVRLHPVILASIVDSYERRNEGAARVIGTLLGTVDKHSVEVTNCFSVPHNESEDEVAVDMEFAKNMYELHKKVSPNELILGWYATGHDITEHSVLIHEYYSREAPNPIHLTVDTSLQNGRMSIKAYVSTLMGVPGRTMGVMFTPLTVRYAYYDTERIGVDLIMKTCFSPNRVIGLSSDLQQVGGASARIQDALSTVLQYAEDVLSGKVSADNTVGRFLMSLVNQVPKIIPDDFETMLNSNINDLLMVTYLANLTQSQIALNEKLVNL.
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For Research Use Only | Not For Clinical Use.
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