Mouse Anti-GRP78 Antibody (MOFAB-106W)
Cat: MOFAB-106W
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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- Product Details
Specifications
| Host species | Mouse |
| Species Reactivity | Human, Mouse, Rat, Bovine, Hamster, Rabbit, Monkey, Xenopus, Fungal |
| Clone | W1H11 |
| Specificity | This antibody recognizes human GRP78. |
| Immunogen | His-tagged human GRP78 |
| Format | Liquid or Lyophilized |
| Buffer | PBS, pH 7.4 |
| Regulatory Status | For Research Use Only |
| Shipping | Gel Pack |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purification | Protein G |
Application Information
| Application | WB, ELISA |
| Application Notes | IB: 0.5-1.0ug/ml The optimal dilution should be determined by the end user. |
Target
| Introduction | GRP78 is a ubiquitously expressed 78kDa glucose-regulated protein commonly referred to as an immunoglobulin chain-binding protein (BiP). BiP is classified as a stress-responsive protein and plays an important role in the folding and assembly of nascent proteins and the clearance of misfolded proteins in the lumen of the endoplasmic reticulum. Translation of BiP is directed by an internal ribosome entry site (IRES) in the 5-untranslated region of BiP mRNA. BIP IRES activity increases when cells are heat stressed. GRP78 is also important in maintaining cellular homeostasis and preventing apoptosis. Decreased levels of GRP78 protein in the brains of Alzheimer's disease patients. |
| Product Overview | The GRP78 antibody is used as Heat Shock and Stress Protein Antibodies. |
| Alternative Names | Heat shock 70kDa protein 5, Fragment; grp78; GRP78 |
| UniProt ID | Q6KDN8 |
See other products for " GRP78 "
| MO-AB-44946W | Mouse Anti-Horse GRP78 Antibody (MO-AB-44946W) |
| MO-AB-11547Y | Mouse Anti-O. mykiss GRP78 Antibody (MO-AB-11547Y) |
| MO-AB-69914W | Mouse Anti-Silkworm grp78 Antibody (MO-AB-69914W) |
| MO-AB-13372R | Mouse Anti-Cattle grp78 Antibody (MO-AB-13372R) |
For Research Use Only | Not For Clinical Use.
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