Mouse Anti-Guinea pig CD19 Antibody (MO-AB-41362W)


Cat: MO-AB-41362W
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityGuinea pig (Cavia porcellus)
CloneMO41362W
SpecificityThis antibody binds to Guinea pig CD19.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationPlasma membrane; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionCD19 (CD19 Molecule) is a Protein Coding gene. Diseases associated with CD19 include Immunodeficiency, Common Variable, 3 and Common Variable Immunodeficiency. Among its related pathways are RET signaling and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. Gene Ontology (GO) annotations related to this gene include signal transducer activity, downstream of receptor.
Product OverviewMouse Anti-Guinea pig CD19 Antibody is a mouse antibody against CD19. It can be used for CD19 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesB-lymphocyte antigen CD19; Differentiation antigen CD19; CD antigen CD19; CD19
UniProt IDP25917
Protein RefseqThe length of the protein is430 amino acids long.
The sequence is show below: NSSDLGDFSCGPGNGSSEGPTPSSQHPNSSQLYVWDKRDSPSWEPEPVCAPPRGSLNENLTQDLTVALGSTLWLSCGVPPAHVTRGPVSWTQVHPKKPDSTLLSLYLREKPPVQEMWVLGPVLSLSQVTVQAAGTYYCLRGNLTTEIHMKVTARQAVWHWLLRSGGWKVPAVSLVYLIFCLGSLVVFLQIRKALVLRRKRKRMTDPNRRFFKVTPPSGNGTPNQYGNVLSLPTPGSSTGRTQRWAAALGGTIQSYGNSRSDVQETGAMGSRSPTTAGIEEEEGEGYEEPDSEEGSEFYENDSNRGQDQLSQDASGYENPEDGPLGSADEDSFSNESYENADEELAQPVARTTDFLSPHGSAWDPSREATSLGSQSYEDMRGILYAAPQLRSLQPGPHHEEDADSYENMDNPDEPEPAWGGGGHMGIWSTR.

Reference

Reference1. Sun, J., Sinkora, J., Wertz, N., Moravkova, A., & Butler, J. E. (2004). Characterization of porcine CD19 and anti-CD19 monoclonal antibodies. Molecular immunology, 41(9), 929-938.
2. Bradbury, L. E., Goldmacher, V. S., & Tedder, T. F. (1993). The CD19 signal transduction complex of B lymphocytes. Deletion of the CD19 cytoplasmic domain alters signal transduction but not complex formation with TAPA-1 and Leu 13. Journal of immunology (Baltimore, Md.: 1950), 151(6), 2915-2927.
3. Tedder, T. F., Inaoki, M., & Sato, S. (1997). The CD19-CD21 complex regulates signal transduction thresholds governing humoral immunity and autoimmunity. Immunity, 6(2), 107-118.
For Research Use Only | Not For Clinical Use.
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