Rabbit Anti-IDE (C-terminal, clone ms2109-029) Antibody (Cat MO-DKB-03621W)
Cat: MO-DKB-03621W
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- Product Details
Specifications
| Host species | Rabbit (Oryctolagus cuniculus) |
| Species Reactivity | Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Zebrafish (Danio rerio) |
| Clone | ms2109-029 |
| Specificity | This antibody is binds to Human Insulin degrading enzyme and has cross reactivity with Mouse, Rat, Zebrafish Insulin degrading enzyme. |
| Immunogen | Human insulin degrading enzyme aa 950 to C-terminal |
| Epitope | C-terminal |
| Format | Liquid or Lyophilized |
| Buffer | TBS, pH 7.4, 1% BSA, 40% Glycerol |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purification | Protein A purified |
Application Information
| Application | WB, IHC-P, IF, IHC |
| Application Notes | Western Blot: 1:300-1000 Immunohistochemistry-Paraffin 1:200-400 Immunofluorescence/Immunocytochemistry: 1:50-200 The optimal dilution should be determined by the end user. |
Target
| Introduction | This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causitive for these diseases. This protein localizes primarily to the cytoplasm but in some cell types localizes to the extracellular space, cell membrane, peroxisome, and mitochondrion. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but have not been experimentally verified.[provided by RefSeq, Sep 2009] |
| Product Overview | This product is a Rabbit antibody against the Insulin degrading enzyme. It can be used for Insulin degrading enzyme detection in Western Blot, Immunohistochemistry-Paraffin, Immunofluorescence, Immunohistochemistry. |
| Alternative Names | Insulin-degrading enzyme; Abeta-degrading protease; Insulin protease; Insulysin; Insulinase; IDE |
| UniProt ID | A4QP10 |
See other products for " IDE "
| MO-AB-31213W | Mouse Anti-Dog IDE Antibody (MO-AB-31213W) |
| MO-AB-57102W | Mouse Anti-Marmoset IDE Antibody (MO-AB-57102W) |
| MO-NAB-00419W | Rabbit Anti-IDE Antibody |
| MO-AB-34671H | Mouse Anti-Tomato ide Antibody (MO-AB-34671H) |
| CBMOAB-00293FYA | Rabbit Anti-Mouse IDE Antibody (CBMOAB-00293FYA) |
| CBMOAB-80244FYA | Mouse Anti-Zebrafish ide Antibody (CBMOAB-80244FYA) |
| MO-DKB-01481W | Rabbit Anti-IDE Antibody (MO-DKB-01481W) |
| CBMOAB-60284FYC | Mouse Anti-Rhesus IDE Antibody (CBMOAB-60284FYC) |
| MO-AB-23092W | Mouse Anti-Chimpanzee IDE Antibody (MO-AB-23092W) |
| CBMOAB-45021FYA | Mouse Anti-Rhesus IDE Antibody (CBMOAB-45021FYA) |
For Research Use Only | Not For Clinical Use.
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