Rabbit Anti-IDE Antibody (MO-DKB-01481W)
Cat: MO-DKB-01481W
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
| Size: | |
| Conjugate: | |
| Inquiry |
- Product Details
Specifications
| Host species | Rabbit (Oryctolagus cuniculus) |
| Species Reactivity | Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Bovine (Bos taurus), Dog (Canis lupus familiaris), Rhesus (Macaca mulatta), Zebrafish (Danio rerio) |
| Immunogen | Recombinant protein containing sequences in the central region of the human IDE. |
| Epitope | The epitope is in the Center of IDE. |
| Format | Liquid or Lyophilized |
| Buffer | PBS, pH 7, 20% Glycerol, 1% BSA |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | Affinity purified |
Application Information
| Application | WB, KO |
| Application Notes | Western Blot 1:500-1:3000 |
Target
| Introduction | This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causitive for these diseases. This protein localizes primarily to the cytoplasm but in some cell types localizes to the extracellular space, cell membrane, peroxisome, and mitochondrion. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but have not been experimentally verified.[provided by RefSeq, Sep 2009] |
| Product Overview | This product is a Rabbit antibody against the Center of the IDE. It can be used for IDE detection in Western Blot, Knockout Validated. |
| Alternative Names | Insulin Degrading Enzyme |
| Gene ID | 3416 |
| UniProt ID | P14735 |
See other products for " IDE "
| CBMOAB-60284FYC | Mouse Anti-Rhesus IDE Antibody (CBMOAB-60284FYC) |
| MO-AB-34671H | Mouse Anti-Tomato ide Antibody (MO-AB-34671H) |
| CBMOAB-20909FYA | Mouse Anti-D. melanogaster Ide Antibody (CBMOAB-20909FYA) |
| MO-AB-31213W | Mouse Anti-Dog IDE Antibody (MO-AB-31213W) |
| MO-NAB-00419W | Rabbit Anti-IDE Antibody |
| MO-DKB-03621W | Rabbit Anti-IDE (C-terminal, clone ms2109-029) Antibody (Cat MO-DKB-03621W) |
| CBMOAB-00293FYA | Rabbit Anti-Mouse IDE Antibody (CBMOAB-00293FYA) |
| MO-AB-57102W | Mouse Anti-Marmoset IDE Antibody (MO-AB-57102W) |
| MO-AB-13937R | Mouse Anti-Cattle IDE Antibody (MO-AB-13937R) |
| CBMOAB-80244FYA | Mouse Anti-Zebrafish ide Antibody (CBMOAB-80244FYA) |
For Research Use Only | Not For Clinical Use.
Online Inquiry